[Reproductive Health-Oriented Development in Assisted Reproductive Technologies].

Q3 Medicine 四川大学学报(医学版) Pub Date : 2024-05-20 DOI:10.12182/20240560401

Peiran Hu, Jiexue Pan, Xinmei Liu, Hefeng Huang

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Abstract

Assisted reproductive technologies (ARTs) are core components of the field of reproductive medicine, encompassing multiple pivotal stages of early development from gamete maturation and fertilization to embryo development. Against the backdrop of a deteriorating trend of global decline in fertility rates, patients with infertility problems increasingly turn to ARTs to realize their dreams of parenthood. However, concomitant with this trend is a growing apprehension regarding the potential adverse effects of ARTs. Herein, we endeavor to discuss several common ARTs procedures utilized in clinical settings and the relevant cutting-edge advancements. The ARTs discussed in the article include in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), biphasic in vitro maturation (biphasic IVM), frozen embryo transfer (FET), preimplantation genetic testing (PGT), non-invasive PGT (niPGT), etc. In addition, we reevaluated their roles within the broader context of assisted reproduction aimed at promoting reproductive health. Additionally, we will delve into the impact of ARTs on the reproductive health of the offspring. By prioritizing the reproductive well-being of both patients and their offspring, the ongoing development and improvement of ARTs to enhance their efficacy and safety will contribute significantly to the advancement of human reproductive health.

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[辅助生殖技术中以生殖健康为导向的发展]。

辅助生殖技术（ART）是生殖医学领域的核心组成部分，涵盖了从配子成熟、受精到胚胎发育等早期发育的多个关键阶段。在全球生育率下降趋势不断恶化的背景下，越来越多的不孕不育患者转而采用辅助生殖技术来实现他们的生育梦想。然而，与这一趋势相伴的是人们对 ARTs 潜在不良影响的担忧与日俱增。在此，我们将努力讨论临床上常用的几种抗逆转录病毒疗法以及相关的前沿进展。文章中讨论的抗逆转录病毒疗法包括体外受精（IVF）、卵胞浆内单精子注射（ICSI）、双相体外成熟（biphasic IVM）、冷冻胚胎移植（FET）、植入前基因检测（PGT）、无创植入前基因检测（niPGT）等。此外，我们还重新评估了它们在旨在促进生殖健康的辅助生殖大背景下的作用。此外，我们还将深入研究抗逆转录病毒疗法对后代生殖健康的影响。通过优先考虑患者及其后代的生殖健康，不断开发和改进抗逆转录病毒疗法以提高其有效性和安全性，将极大地促进人类生殖健康的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

四川大学学报(医学版) Biochemistry, Genetics and Molecular Biology-Molecular Biology

CiteScore

0.70

自引率

0.00%

发文量

8695

期刊介绍： "Journal of Sichuan University (Medical Edition)" is a comprehensive medical academic journal sponsored by Sichuan University, a higher education institution directly under the Ministry of Education of the People's Republic of China. It was founded in 1959 and was originally named "Journal of Sichuan Medical College". In 1986, it was renamed "Journal of West China University of Medical Sciences". In 2003, it was renamed "Journal of Sichuan University (Medical Edition)" (bimonthly). "Journal of Sichuan University (Medical Edition)" is a Chinese core journal and a Chinese authoritative academic journal (RCCSE). It is included in the retrieval systems such as China Science and Technology Papers and Citation Database (CSTPCD), China Science Citation Database (CSCD) (core version), Peking University Library's "Overview of Chinese Core Journals", the U.S. "Index Medica" (IM/Medline), the U.S. "PubMed Central" (PMC), the U.S. "Biological Abstracts" (BA), the U.S. "Chemical Abstracts" (CA), the U.S. EBSCO, the Netherlands "Abstracts and Citation Database" (Scopus), the Japan Science and Technology Agency Database (JST), the Russian "Abstract Magazine", the Chinese Biomedical Literature CD-ROM Database (CBMdisc), the Chinese Biomedical Periodical Literature Database (CMCC), the China Academic Journal Network Full-text Database (CNKI), the Chinese Academic Journal (CD-ROM Edition), and the Wanfang Data-Digital Journal Group.