Silica nanoparticle design for colorectal cancer treatment: Recent progress and clinical potential.

IF 2.6 Q3 ONCOLOGY World journal of clinical oncology Pub Date : 2024-06-24 DOI:10.5306/wjco.v15.i6.667
Jin Meng, Zhi-Gang Wang, Xiu Zhao, Ying Wang, De-Yu Chen, De-Long Liu, Cheng-Chun Ji, Tian-Fu Wang, Li-Mei Zhang, Hai-Xia Bai, Bo-Yang Li, Yuan Liu, Lei Wang, Wei-Gang Yu, Zhi-Tao Yin
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Abstract

Colorectal cancer (CRC) is the third most common cancer worldwide and the second most common cause of cancer death. Nanotherapies are able to selectively target the delivery of cancer therapeutics, thus improving overall antitumor efficiency and reducing conventional chemotherapy side effects. Mesoporous silica nanoparticles (MSNs) have attracted the attention of many researchers due to their remarkable advantages and biosafety. We offer insights into the recent advances of MSNs in CRC treatment and their potential clinical application value.

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用于结直肠癌治疗的二氧化硅纳米粒子设计:最新进展和临床潜力。
结直肠癌(CRC)是全球第三大常见癌症,也是第二大常见癌症死因。纳米疗法能够选择性地靶向输送癌症治疗药物,从而提高整体抗肿瘤效率并减少传统化疗的副作用。介孔二氧化硅纳米粒子(MSN)因其显著的优势和生物安全性吸引了众多研究人员的关注。我们将深入探讨介孔二氧化硅纳米颗粒在治疗 CRC 方面的最新进展及其潜在的临床应用价值。
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期刊介绍: The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.
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