[Progress in Lymphangiogenesis and Lymphatic Metastasis of Thyroid Carcinoma].

Xu Li, Yan Zhang
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Abstract

Thyroid carcinoma is a common endocrine malignancy,with most cases being indolent.Lymphatic metastasis as a representative metastasis type defines the clinical stage and prognosis of thyroid carcinoma.The mechanism of lymphatic metastasis in malignancies has been a research hotspot for years,and certain progress being achieved.This article reviews the molecular markers of lymphatic vessels and their application in diagnosis and treatment of neoplasms,the mechanism and role of lymphangiogenesis in lymphatic metastasis,the tracing methods for sentinel lymph nodes by lymphatic drainage,and the use of ultrasound in cervical lymph node metastasis of thyroid carcinoma.Especially,this paper details the application of conventional ultrasound,transvenous contrast-enhanced ultrasound,and trans-lymphatic contrast-enhanced ultrasound in cervical lymph node metastasis of thyroid carcinoma.

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[甲状腺癌淋巴管生成和淋巴转移研究进展]。
甲状腺癌是一种常见的内分泌恶性肿瘤,多数病例呈隐匿性。淋巴转移作为一种代表性的转移类型,决定了甲状腺癌的临床分期和预后。多年来,恶性肿瘤淋巴转移的机制一直是研究的热点,并取得了一定的进展。本文综述了淋巴管的分子标记及其在肿瘤诊治中的应用、淋巴管生成在淋巴转移中的机制和作用、淋巴引流的前哨淋巴结追踪方法以及超声在甲状腺癌颈淋巴结转移中的应用。本文特别详细介绍了常规超声、经静脉造影剂增强超声和经淋巴管造影剂增强超声在甲状腺癌颈淋巴结转移中的应用。
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来源期刊
中国医学科学院学报
中国医学科学院学报 Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
6813
期刊介绍: Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].
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