Gastrointestinal and Neuropsychological Symptoms Are Associated With Distinct Vomiting Profiles in Patients Receiving Chemotherapy.

IF 1.6 4区 医学 Q2 NURSING Oncology nursing forum Pub Date : 2024-06-14 DOI:10.1188/24.ONF.361-380
Komal P Singh, Bruce A Cooper, Steven M Paul, Kathryn Ruddy, Amrit B Singh, Jun Chen, Keenan A Pituch, Tom E Grys, Parminder Singh, Felipe Batalini, Marilyn J Hammer, Jon D Levine, Christine Miaskowski
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Abstract

Objectives: To identify subgroups of patients with distinct chemotherapy-induced vomiting (CIV) profiles; determine how these subgroups differ on several demographic, clinical, and symptom characteristics; and evaluate factors associated with chemotherapy-induced nausea and CIV profiles.

Sample & setting: Adult patients (N = 1,338) receiving cancer chemotherapy.

Methods & variables: Data were collected on demographic, clinical, and symptom characteristics. Differences among subgroups of patients with distinct CIV profiles were evaluated using parametric and nonparametric tests.

Results: Three CIV profiles (None, Decreasing, and Increasing) were identified. Compared with the None class, Decreasing and Increasing classes were more likely to have lower household income and a higher comorbidity burden, as well as to report higher rates of dry mouth, nausea, diarrhea, depression, anxiety, sleep disturbance, morning fatigue, and pain interference.

Implications for nursing: Clinicians need to assess common and distinct risk factors for CIV and chemotherapy-induced nausea.

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化疗患者的胃肠道症状和神经心理学症状与不同的呕吐特征有关。
目的:确定具有不同化疗诱发呕吐(CIV)特征的患者亚群;确定这些亚群在人口统计学、临床和症状特征方面的差异;评估与化疗诱发呕吐相关的因素:确定具有不同化疗诱发呕吐(CIV)特征的患者亚组;确定这些亚组在人口统计学、临床和症状特征方面的差异;评估与化疗诱发恶心和CIV特征相关的因素:方法与变量:方法与变量:收集有关人口统计学、临床和症状特征的数据。采用参数检验和非参数检验评估了具有不同 CIV 特征的患者亚组之间的差异:结果:确定了三种 CIV 特征(无、减少和增加)。与 "无 "类相比,"减少 "类和 "增加 "类患者的家庭收入更低,合并症负担更重,口干、恶心、腹泻、抑郁、焦虑、睡眠障碍、晨起疲劳和疼痛干扰的发生率更高:临床医生需要评估CIV和化疗诱发恶心的常见和独特风险因素。
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来源期刊
Oncology nursing forum
Oncology nursing forum 医学-护理
CiteScore
3.20
自引率
0.00%
发文量
76
审稿时长
>12 weeks
期刊介绍: The mission of the Oncology Nursing Forum, an official publication of ONS, is to Convey research information related to practice, technology, education, and leadership. Disseminate oncology nursing research and evidence-based practice to enhance transdisciplinary quality cancer care. Stimulate discussion of critical issues relevant to oncology nursing.
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