Proportion and risk factors of low birth weight among neonates delivered at Omdurman Maternity Hospital, Sudan.

Ahmed Abdallah Ali Mahmoud, Kamil Shaaban, Ahmed Abdulgadir Noureddin, Sagad Omer Obeid Mohamed, Mohammed Almojtaba Mahdy Abdalrahman Abdalhameed, Khalefa Badreldeen Khalefa Elzubeir, Mohammed Atif Hassan Mohammednoor, Elsara Mohamed Ali Mirghani
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Abstract

Low birth weight (LBW) is a major predictor of child mortality and morbidity. The objectives of this study are to determine the proportion and risk factors of LBW. A matched case-control study was conducted at Omdurman Maternity Hospital, Sudan. The study population consisted of all babies delivered in August 2016 excluding stillbirths, multiple births, and babies with insufficient data. All LBW neonates were selected using total coverage sampling as cases and matched on babies' gender with randomly selected normal birth weights as controls. The sample size was 350 babies; 175 test cases and 175 control cases. Data were collected from hospital records and six risk factors were tested: mother age, parity, gravidity, mode of delivery, hypertensive disorders, and diabetes mellitus. The proportion of LBW was 10.8% of the total number of delivered neonates which is 2,938. The bivariate analysis identified that younger mother age (p = 0.03) and hypertension (p = 0.02) were significantly associated with LBW while other factors were found statistically insignificant. Multivariable conditional logistic regression revealed that hypertensive disorders in pregnancy increase the risk for LBW almost three times [Adjusted OR = 2.98 (95% CI: 1.23-7.22), p = 0.02]. We found that hypertension is an independent risk factor for LBW. The proportion of LBWcan be reduced if hypertension is controlled by providing simple measures like proper antenatal care and health education for pregnant women.

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苏丹乌姆杜尔曼妇产医院新生儿出生体重不足的比例和风险因素。
低出生体重(LBW)是预测儿童死亡率和发病率的一个主要因素。本研究旨在确定低出生体重儿的比例和风险因素。在苏丹乌姆杜尔曼妇产医院进行了一项匹配病例对照研究。研究人群包括2016年8月分娩的所有婴儿,不包括死胎、多胎和数据不充分的婴儿。采用全覆盖抽样法选取所有低体重新生儿作为病例,并根据婴儿性别与随机选取的正常出生体重婴儿进行配对作为对照。样本量为 350 个婴儿,其中 175 个为测试病例,175 个为对照病例。数据收集自医院记录,并对六个风险因素进行了检测:母亲年龄、胎次、孕产妇、分娩方式、高血压疾病和糖尿病。在 2 938 名分娩的新生儿中,低体重儿的比例为 10.8%。双变量分析表明,母亲年龄较小(p = 0.03)和高血压(p = 0.02)与低体重儿显著相关,而其他因素在统计学上并不重要。多变量条件逻辑回归显示,妊娠期高血压疾病会使婴儿夭折的风险增加近三倍[调整后 OR = 2.98 (95% CI: 1.23-7.22),p = 0.02]。我们发现,高血压是导致低体重儿的一个独立风险因素。如果采取简单的措施,如适当的产前护理和对孕妇进行健康教育,就能控制高血压,从而降低低体重儿的比例。
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