Artificial intelligence on breast cancer risk prediction

João Mendes , Bernardo Oliveira , Carolina Araújo , Joana Galrão , Nuno C. Garcia , Nuno Matela
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Abstract

Breast Cancer is currently the most commonly diagnosed type of cancer worldwide. While the impacts of this disease can be mitigated through early diagnosis, generalized screening programs based on full-field digital mammography present several limitations regarding lesion obscurity and false positive diagnosis. Given that, women could benefit from a risk analysis for the development of BC that would allow their healthcare professionals to adapt screening in a personalized fashion, not only in terms of frequency but also regarding the imaging modality used. This study aims to develop a medical application, based on Artificial Intelligence (AI), that receives images from different modalities as input and outputs a personalized risk prediction for BC development. The final goal is to have an AI model that allocates each analyzed case to a risk group (1/2-year risk, 3/4-year risk, 5/more-year risk) based on characteristics present in the medical images. A solution like the one proposed would allow not only the previously mentioned screening adaptation but also some preventive measures taken both by the healthcare professional and by the patient. Finally, the development of a computerized medical application allows its use in any type of medical facility, despite the socio-economical characteristics of the patients.

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人工智能预测乳腺癌风险
乳腺癌是目前全球最常见的癌症类型。虽然这种疾病的影响可以通过早期诊断得到缓解,但基于全视野数字乳腺 X 射线照相术的普查计划在病变不明显和假阳性诊断方面存在一些局限性。有鉴于此,妇女可受益于乳腺癌发病风险分析,这将使她们的医疗保健专业人员能够以个性化的方式调整筛查,不仅在频率方面,而且在使用的成像模式方面。本研究旨在开发一款基于人工智能(AI)的医疗应用程序,该应用程序可接收来自不同模式的图像作为输入,并输出针对 BC 发展的个性化风险预测。最终目标是建立一个人工智能模型,根据医学影像中的特征将每个分析病例分配到一个风险组(1/2 年风险、3/4 年风险、5 年以上风险)。类似的解决方案不仅可以进行前面提到的筛查调整,还可以由医疗专业人员和患者采取一些预防措施。最后,计算机化医疗应用程序的开发允许在任何类型的医疗机构中使用,尽管病人的社会经济特征各不相同。
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