{"title":"Low-Density lipoprotein cholesterol goal achievement and associated factors among type 2 diabetes mellitus patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia: Cross-sectional Study, 2023","authors":"Abdisa Beyene , Teshome Habte , Aklil Hailu","doi":"10.1016/j.ijans.2024.100737","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Achieving the recommended low-density lipoprotein cholesterol goal is vital for managing cardiovascular risk. However, research on low-density lipoprotein cholesterol goal achievement and associated factors in Sub-Saharan Africa, particularly in Ethiopia, is limited. While global rates vary from 18% to 73%, there is a need for further investigation in this region to better understand and address the factors influencing low-density lipoprotein cholesterol goal attainment.</p><p>The objective was to assess low-density lipoprotein cholesterol goal achievement and associated factors among type 2 diabetes patients.</p></div><div><h3>Methods</h3><p>Institution based quantitative cross-sectional study design was conducted among type II diabetes patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia.</p><p>Systematic random sampling technique was used to select patient records. Data was collected by using a structured and pretested checklist and some variables were also collected from the chart review, structured questionnaire and analyzed using Epi info version 7.2 and SPSS version 25. Bivariate and multivariable logistic regressions were performed to examine the association between variables. Adjusted odds ratios (AOR) with 95 % confidence intervals were calculated, and a p-value of ≤ 0.05 was considered statistically significant for associations between independent and outcome variables.</p></div><div><h3>Result</h3><p>The LDL goal achievement among type II diabetes patients is 58.9 %.Total triglyceride level (AOR = 0.19, 95 %CI, 0.12, 0.54, P= <0.0001), history of smoking (AOR = 0.198, 95 %CI, 1.06, 1.10, P < 0.0001), 40–65 years of age (AOR = 0.21, 95 %CI, 0.05, 0.87, P = 0.03), BMI (AOR = 0.19, 95 %CI, 0.12, 0.54, P= <0.0001)., were found to be statistically significant independent predictors for LDL Goal Achievement in type II Diabetes patients.</p></div><div><h3>Conclusion</h3><p>In the current study, significant proportions of type II DM patients fail to attain acceptable levels of LDL cholesterol. Factors like total triglyceride levels, smoking history, older age, and increased BMI influenced low-density lipoprotein cholesterol goal achievement. Advanced in age, increase in BMI, smoking, and higher levels of triglyceride were determinants of LDL cholesterol goal achievement. Patient education on life style modification mainly cessation of smoking diet and exercise may be recommended to achieve the LDL cholesterol goal.</p></div>","PeriodicalId":38091,"journal":{"name":"International Journal of Africa Nursing Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214139124000829/pdfft?md5=dd1e78890abe7651f0e1bf67bec544fc&pid=1-s2.0-S2214139124000829-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Africa Nursing Sciences","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214139124000829","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Achieving the recommended low-density lipoprotein cholesterol goal is vital for managing cardiovascular risk. However, research on low-density lipoprotein cholesterol goal achievement and associated factors in Sub-Saharan Africa, particularly in Ethiopia, is limited. While global rates vary from 18% to 73%, there is a need for further investigation in this region to better understand and address the factors influencing low-density lipoprotein cholesterol goal attainment.
The objective was to assess low-density lipoprotein cholesterol goal achievement and associated factors among type 2 diabetes patients.
Methods
Institution based quantitative cross-sectional study design was conducted among type II diabetes patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia.
Systematic random sampling technique was used to select patient records. Data was collected by using a structured and pretested checklist and some variables were also collected from the chart review, structured questionnaire and analyzed using Epi info version 7.2 and SPSS version 25. Bivariate and multivariable logistic regressions were performed to examine the association between variables. Adjusted odds ratios (AOR) with 95 % confidence intervals were calculated, and a p-value of ≤ 0.05 was considered statistically significant for associations between independent and outcome variables.
Result
The LDL goal achievement among type II diabetes patients is 58.9 %.Total triglyceride level (AOR = 0.19, 95 %CI, 0.12, 0.54, P= <0.0001), history of smoking (AOR = 0.198, 95 %CI, 1.06, 1.10, P < 0.0001), 40–65 years of age (AOR = 0.21, 95 %CI, 0.05, 0.87, P = 0.03), BMI (AOR = 0.19, 95 %CI, 0.12, 0.54, P= <0.0001)., were found to be statistically significant independent predictors for LDL Goal Achievement in type II Diabetes patients.
Conclusion
In the current study, significant proportions of type II DM patients fail to attain acceptable levels of LDL cholesterol. Factors like total triglyceride levels, smoking history, older age, and increased BMI influenced low-density lipoprotein cholesterol goal achievement. Advanced in age, increase in BMI, smoking, and higher levels of triglyceride were determinants of LDL cholesterol goal achievement. Patient education on life style modification mainly cessation of smoking diet and exercise may be recommended to achieve the LDL cholesterol goal.
期刊介绍:
International Journal of Africa Nursing Sciences (IJANS) is an international scientific journal published by Elsevier. The broad-based journal was founded on two key tenets, i.e. to publish the most exciting research with respect to the subjects of Nursing and Midwifery in Africa, and secondly, to advance the international understanding and development of nursing and midwifery in Africa, both as a profession and as an academic discipline. The fully refereed journal provides a forum for all aspects of nursing and midwifery sciences, especially new trends and advances. The journal call for original research papers, systematic and scholarly review articles, and critical papers which will stimulate debate on research, policy, theory or philosophy of nursing as related to nursing and midwifery in Africa, technical reports, and short communications, and which will meet the journal''s high academic and ethical standards. Manuscripts of nursing practice, education, management, and research are encouraged. The journal values critical scholarly debate on issues that have strategic significance for educators, practitioners, leaders and policy-makers of nursing and midwifery in Africa. The journal publishes the highest quality scholarly contributions reflecting the diversity of nursing, and is also inviting international scholars who are engaged with nursing and midwifery in Africa to contribute to the journal. We will only publish work that demonstrates the use of rigorous methodology as well as by publishing papers that highlight the theoretical underpinnings of nursing and midwifery as it relates to the Africa context.