Toxicological risks of dairy proteins produced through cellular agriculture: Current state of knowledge, challenges and future perspectives

IF 7.2 Q1 FOOD SCIENCE & TECHNOLOGY Future Foods Pub Date : 2024-06-27 DOI:10.1016/j.fufo.2024.100412
Vaios D. Fytsilis , Miriam J.E. Urlings , Frederik-Jan van Schooten , Alie de Boer , Misha F. Vrolijk
{"title":"Toxicological risks of dairy proteins produced through cellular agriculture: Current state of knowledge, challenges and future perspectives","authors":"Vaios D. Fytsilis ,&nbsp;Miriam J.E. Urlings ,&nbsp;Frederik-Jan van Schooten ,&nbsp;Alie de Boer ,&nbsp;Misha F. Vrolijk","doi":"10.1016/j.fufo.2024.100412","DOIUrl":null,"url":null,"abstract":"<div><p>The growing population and the associated increasing demand for high-protein meals are the main drivers of the protein transition. To meet demand, the food industry has turned to new technologies, such as food production through cell culture methods, also known as cellular agriculture. The interest in cellular agriculture is rising, and more products produced this way are seeking regulatory approval, including cell-based dairy products.</p><p>This review explores the potential toxicological challenges that may arise from cell-based dairy production, in regards to human consumption. The purpose is to identify knowledge gaps and elucidate an inscrutable field. The major production routes are described and analyzed regarding potential safety concerns and the current state of the industry. An in-depth look into the EU regulatory requirements concerning these foods is offered, along with a detailed overview of the potential risks and ways to assess them, focused on new approach methodologies (NAMs).</p><p>Cellular agriculture presents novel advantages and disadvantages in regard to food safety. To assess these novel risks, both regulatory and toxicological sciences need to adapt in order to keep up with innovations in food production. The advancement and integration of NAMs in food safety assessment is a crucial step to achieving this goal.</p></div>","PeriodicalId":34474,"journal":{"name":"Future Foods","volume":"10 ","pages":"Article 100412"},"PeriodicalIF":7.2000,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666833524001187/pdfft?md5=c2f234fffb70307fcda886837b45006b&pid=1-s2.0-S2666833524001187-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Foods","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666833524001187","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

The growing population and the associated increasing demand for high-protein meals are the main drivers of the protein transition. To meet demand, the food industry has turned to new technologies, such as food production through cell culture methods, also known as cellular agriculture. The interest in cellular agriculture is rising, and more products produced this way are seeking regulatory approval, including cell-based dairy products.

This review explores the potential toxicological challenges that may arise from cell-based dairy production, in regards to human consumption. The purpose is to identify knowledge gaps and elucidate an inscrutable field. The major production routes are described and analyzed regarding potential safety concerns and the current state of the industry. An in-depth look into the EU regulatory requirements concerning these foods is offered, along with a detailed overview of the potential risks and ways to assess them, focused on new approach methodologies (NAMs).

Cellular agriculture presents novel advantages and disadvantages in regard to food safety. To assess these novel risks, both regulatory and toxicological sciences need to adapt in order to keep up with innovations in food production. The advancement and integration of NAMs in food safety assessment is a crucial step to achieving this goal.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
通过细胞农业生产的乳制品蛋白质的毒理学风险:知识现状、挑战和未来展望
不断增长的人口和与之相关的对高蛋白膳食日益增长的需求是蛋白质转型的主要驱动力。为满足需求,食品工业已转向新技术,如通过细胞培养方法生产食品,也称为细胞农业。人们对细胞农业的兴趣日益高涨,越来越多以这种方式生产的产品正在寻求监管部门的批准,其中包括基于细胞的乳制品。本综述探讨了基于细胞的乳制品生产可能给人类消费带来的潜在毒理学挑战。本综述探讨了细胞乳制品生产在人类消费方面可能出现的潜在毒理学挑战,目的是找出知识差距,阐明这一难以捉摸的领域。就潜在的安全问题和行业现状对主要的生产途径进行了描述和分析。报告深入探讨了欧盟对这些食品的监管要求,并详细概述了潜在风险和评估风险的方法,重点介绍了新方法(NAMs)。为了评估这些新风险,监管科学和毒理学都需要进行调整,以跟上食品生产的创新步伐。在食品安全评估中推进和整合 NAM 是实现这一目标的关键一步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Future Foods
Future Foods Agricultural and Biological Sciences-Food Science
CiteScore
8.60
自引率
0.00%
发文量
97
审稿时长
15 weeks
期刊最新文献
Mechanistic insights to the strong antioxidative capacity of lingonberry press cake during recovery of fish protein ingredients Resource use efficiency: Developing a generic framework for protein production systems and its application on dairy and fish New fermented plant-based ingredients in sourdough breads enhanced nutritional value and impacted on gut microbiota Whey protein-based bigels for co-encapsulation of curcumin and gallic acid: Characterization, stability and release kinetics Fat replacers in food system: A focus on ingredients, fabrication methods, and applications in food products
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1