Katherine Elizabeth Quiohilag, Carol Kwon, Jonathan GN. Davey, David Andrew Dorward
{"title":"A morphology-based approach to mesenchymal tumours of the thorax","authors":"Katherine Elizabeth Quiohilag, Carol Kwon, Jonathan GN. Davey, David Andrew Dorward","doi":"10.1016/j.mpdhp.2024.04.005","DOIUrl":null,"url":null,"abstract":"<div><p>Primary mesenchymal tumours of the thorax are rare lesions that can pose significant diagnostic difficulties, particularly given the morphological overlap with carcinomas and mesotheliomas that occur much more commonly at these sites. In this article we will discuss a morphology-based approach to assist pathologists when confronted with a possible mesenchymal neoplasm. This will be combined with an overview of the key immunohistochemical and molecular studies that aid diagnosis of the more commonly encountered neoplasms that arise in the thorax.</p></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"30 7","pages":"Pages 386-397"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231724000537","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Primary mesenchymal tumours of the thorax are rare lesions that can pose significant diagnostic difficulties, particularly given the morphological overlap with carcinomas and mesotheliomas that occur much more commonly at these sites. In this article we will discuss a morphology-based approach to assist pathologists when confronted with a possible mesenchymal neoplasm. This will be combined with an overview of the key immunohistochemical and molecular studies that aid diagnosis of the more commonly encountered neoplasms that arise in the thorax.
期刊介绍：
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.
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