Trends in hip fracture rates in spain from 2001 to 2018.

IF 3.1 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Archives of Osteoporosis Pub Date : 2024-07-03 DOI:10.1007/s11657-024-01406-2
D Toledo, J Mayordomo-Cava, P Jurado, A Díaz, J A Serra-Rexach
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Abstract

The present study includes the longest period of analysis with the highest number of hip fracture episodes (756,308) described in the literature for Spain. We found that the age-adjusted rates progressively decreased from 2005 to 2018. We believe that this is significant because it may mean that measures such as prevention and treatment of osteoporosis, or programs promoting healthy lifestyles, have had a positive impact on hip fracture rates.

Purpose: To describe the evolution of cases and rates of hip fracture (HF) in patients 65 years or older in Spain from 2001 to 2018 and examine trends in adjusted rates.

Methods: Retrospective, observational study including patients ≥65 years with acute HF. Data from 2001 to 2018 were obtained from the Spanish National Record of the Minimum Basic Data Set of the Ministry of Health. We analysed cases of HF, crude incidence and age-adjusted rates by sex, length of hospital stay (LOS) and in-hospital mortality, and used joinpoint regression analysis to explore temporal trends.

Results: We identified 756,308 HF cases. Mean age increased 2.5 years, LOS decreased 4.5 days and in-hospital mortality was 5.5-6.5%. Cases of HF increased by 49%. Crude rate per 100,000 was 533.3 (95% confidence interval [CI], 532.1-534.5), increasing 14.0% (95%CI, 13.7-14.2). Age-adjusted HF incidence rate increased by 6.9% from 2001 (535.7; 95%CI, 529.9-541.5) to 2005 (572.4; 95%CI, 566.7-578.2), then decreased by 13.3% until 2017 (496.1, 95%CI, 491.7-500.6). Joinpoint regression analysis indicated a progressive increase in age-adjusted incidence rates of 1.9% per year from 2001 to 2005 and a progressive decrease of -1.1% per year from 2005 to 2018. A similar pattern was identified in both sexes.

Conclusions: Crude incidence rates of HF in Spain in persons ≥65 years from 2001 to 2018 have gradually increased. Age-adjusted rates show a significant increase from 2001 to 2005 and a progressive decrease from 2005 to 2018.

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2001 年至 2018 年西班牙髋部骨折发病率趋势。
本研究包括了文献中描述的西班牙髋部骨折发作次数最多(756308 次)的最长分析期。我们发现,从 2005 年到 2018 年,年龄调整后的发病率逐渐下降。我们认为这具有重要意义,因为这可能意味着预防和治疗骨质疏松症等措施或促进健康生活方式的计划对髋部骨折发生率产生了积极影响。目的:描述 2001 年至 2018 年西班牙 65 岁或以上患者髋部骨折(HF)病例和发生率的演变情况,并研究调整后发生率的趋势:回顾性观察研究,包括≥65岁的急性高血压患者。2001年至2018年的数据来自西班牙卫生部的西班牙国家最低基本数据集记录。我们按性别、住院时间(LOS)和院内死亡率分析了高血压病例、粗发病率和年龄调整率,并使用连接点回归分析探讨了时间趋势:我们发现了 756,308 例高血压病例。平均年龄增加了 2.5 岁,住院时间缩短了 4.5 天,院内死亡率为 5.5%-6.5%。心房颤动病例增加了 49%。每十万人的粗发病率为 533.3(95% 置信区间 [CI],532.1-534.5),增加了 14.0%(95%CI,13.7-14.2)。年龄调整后的心房颤动发病率从2001年(535.7;95%CI,529.9-541.5)到2005年(572.4;95%CI,566.7-578.2)上升了6.9%,然后到2017年(496.1,95%CI,491.7-500.6)下降了13.3%。连接点回归分析表明,2001年至2005年,年龄调整后的发病率每年递增1.9%,2005年至2018年,发病率每年递减-1.1%。男女发病模式相似:2001年至2018年,西班牙≥65岁人群的心房颤动粗发病率逐渐上升。年龄调整后的发病率显示,2001 年至 2005 年显著上升,2005 年至 2018 年逐渐下降。
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来源期刊
Archives of Osteoporosis
Archives of Osteoporosis ENDOCRINOLOGY & METABOLISMORTHOPEDICS -ORTHOPEDICS
CiteScore
5.50
自引率
10.00%
发文量
133
期刊介绍: Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
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