Ductal Carcinoma In Situ

IF 2.5 3区 医学 Q2 HEMATOLOGY Hematology-Oncology Clinics of North America Pub Date : 2024-07-01 DOI:10.1016/j.hoc.2024.05.014
Brittany L. Bychkovsky MD, MSc , Sara Myers MD, PhD , Laura E.G. Warren MD , Pietro De Placido MD , Heather A. Parsons MD, MPH
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原位导管癌
在乳腺癌(BC)发病模型中,正常细胞会发生体细胞突变,从高危病变和导管原位癌逐步发展为浸润性癌症。乳腺组织的癌前生物学特性需要更好的描述,以了解不同的乳腺癌亚型是如何出现的。预防乳腺癌或降低风险的主要方法包括改变生活方式、手术和化学预防。预防乳腺癌的手术干预包括降低风险的预防性乳房切除术,通常与原发性肿瘤的治疗同步进行,或在高风险妇女中作为双侧手术进行。使用内分泌疗法进行化学预防会产生依赖性毒性。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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