Synthesis of β-phosphonomalonates using a recyclable choline hydroxide catalyst

IF 1.8 3区 化学 Q3 CHEMISTRY, ORGANIC Synthetic Communications Pub Date : 2024-07-02 DOI:10.1080/00397911.2024.2368771
Reddi Mohan Naidu Kalla , M. Varalakshmi , C. Raju , Jaewoong Lee
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Abstract

Choline hydroxide (ChOH) is an effective ionic liquid (IL) that enables the straightforward construction of β-phosphonomalonates in basic medium. A variety of compounds, including aromatic/heterocyclic and aliphatic aldehydes (1a–p) were reacted with dicyanomethane (2) and diethyl phosphonate (3) to produce the targeted products in good yields (4a–p). The constructed compounds as well as the IL were characterized using spectral 1H, 13C, and 31P NMR.

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使用可回收氢氧化胆碱催化剂合成 β-磷酰丙二酸盐
氢氧化胆碱 (ChOH) 是一种有效的离子液体 (IL),可在碱性介质中直接构建 β-磷酰丙二酸盐。多种化合物,包括芳香族/杂环族化合物、...
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来源期刊
Synthetic Communications
Synthetic Communications 化学-有机化学
CiteScore
4.40
自引率
4.80%
发文量
156
审稿时长
4.3 months
期刊介绍: Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.
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