Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients

Abstract

To the Editor,

Kaddah and colleagues [1] in their recently released study, employed metabolic syndrome definition elements (MetSDE) of the International Diabetes Federation (IDF) to study MetS prevalence and its predictors in Egyptian patients with obstructive sleep apnea (OSA). They found that 66.3% of OSA patients exhibited MetS and the relevant MetS predictors were SPO2 < 90%, body mass index, and neck, hip, and waist circumferences [1]. In addition to the few limitations addressed by Kaddah and colleagues [1], we present a noteworthy limitation, which is linked to MetSDE employed in the research. The optimum definition of MetS remains controversial. Over several years, numerous MetS definitions have been developed by scientific bodies. Though these definitions vary to some degree in their elements and threshold values, they generally endorse the essential parameters of the syndrome, notably abdominal obesity, dyslipidemia, hypertension, and insulin resistance. In research and clinical fields, numerous MetSDE are usually used such as IDF, American Heart Association (AHA), adult treatment panel-III (ATP-III), and finally joint interim statement (JIS). There is a significant conflicting agreement on the accuracy of these MetSDE for MetS characterization as noticed by numerous observational studies [2, 3]. Different results were obtained when measuring MetS prevalence among adult Egyptians using various MetSDE, namely 44.3% (IDF elements), 43.8% (AHA elements), 42.5% (ATP-III elements), and 41.5% (JIS elements with Egyptian cut-offs) [4]. To overcome the variations in estimating MetS prevalence by using different MetSDE, numerous nations have developed their diagnostic MetSDE and proved effective in yielding validated results in research and practice [5, 6]. The formulation of the Egyptian MetSDE is deemed critical as it can measure more readily MetS prevalence in OSA patients. Regardless of the study limitations, the recorded MetS prevalence in the studied OSA patients (66.3%) [1] is troublesome and it calls for the urgent implementation of strategic interventions to lessen the negative health effects of MetS, decrease healthcare visits and costs, and improve OSA patients’ quality of life.

IDF:

International Diabetes Federation

OSA:

Obstructive sleep apnea

MetS:

Metabolic syndrome

MetSDE:

MetS definition elements

AHA:

American Heart Association

ATP-III:

Adult Treatment Panel-III

JI:

Joint Interim Statement

1. Kaddah SZ, Korany MH, Ibrahim EK (2024) Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients. Egypt J Bronchol 18:6

   Article Google Scholar

2. Nwankwo M, Okamkpa CJ, Danborno B (2022) Comparison of diagnostic criteria and prevalence of metabolic syndrome using WHO, NCEP-ATP III, IDF and harmonized criteria: a case study from urban southeast Nigeria. Diabetes Metab Syndr 16(12):102665

   Article CAS PubMed Google Scholar

3. de Almeida MD, Dos Santos AM, da Cruz Silveira VN, Silva MB, da Silva DA (2023) Prevalence of metabolic syndrome in adolescents based on three diagnostic definitions: a cross-sectional study. Arch Endocrinol Metab 67(5):e000634

   Article Google Scholar

4. Assaad-Khalil SH, Mikhail MM, Aati TA, Zaki A, Helmy MA, Megallaa MH et al (2015) Optimal waist circumference cutoff points for the determination of abdominal obesity and detection of cardiovascular risk factors among adult Egyptian population. Indian J Endocrinol Metab 19(6):804–810

   Article CAS PubMed PubMed Central Google Scholar

5. Ding Z, Pi F, Zhang S, Dong W, Wen Y, Wu J, Zhang Q (2016) Establishment and application of a new diagnostic definition of metabolic syndrome in the Shantou region of southern China. Sci Rep 6:22210

   Article CAS PubMed PubMed Central Google Scholar

6. Yamagishi K, Iso H (2017) The criteria for metabolic syndrome and the national health screening and education system in Japan. Epidemiol Health 39:e2017003

   Article PubMed PubMed Central Google Scholar

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Authors and Affiliations

1. Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

   Mahmood D. Al-Mendalawi

2. Baghdad Post Office, P.O.Box 55302, Baghdad, Iraq

   Mahmood D. Al-Mendalawi

Authors

1. Mahmood D. Al-MendalawiView author publications

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MDA read the literature on metabolic syndrome and obstructive sleep apnea, wrote the manuscript, and approved it.

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Correspondence to Mahmood D. Al-Mendalawi.

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MDA states that he has no competing interests.

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Al-Mendalawi, M.D. Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients. Egypt J Bronchol 18, 42 (2024). https://doi.org/10.1186/s43168-024-00296-9

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• Received: 07 February 2024

• Accepted: 16 June 2024

• Published: 20 June 2024

• DOI: https://doi.org/10.1186/s43168-024-00296-9

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