Comparison Between Black Non-Hispanic and White Non-Hispanic Simultaneous Pancreas-Kidney Transplant Candidates and Recipients

IF 1.9 4区 医学 Q2 SURGERY Clinical Transplantation Pub Date : 2024-07-05 DOI:10.1111/ctr.15392
Shawna M. Green, Aaron C. Spaulding, Emily R. Brennan, Tambi Jarmi
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Abstract

Introduction

This study examined simultaneous pancreas–kidney transplant (SPKt) in Black and White patients to identify disparities in transplantation, days on the waitlist, and reasons for SPKt waitlist removal.

Methods

Using the United Network for Organ Sharing Standard Transplant Analysis and Research file, patients between January 1, 2009, and May 31, 2021, were included. Three cohorts (overall, SPKt recipients only, and those not transplanted) were selected using propensity score matching. Conditional logistic regression was used for categorical outcomes. Days on the waitlist were compared using negative binomial regression.

Results

Black patients had increased odds of receiving a  SPKt (OR, 1.25 [95% CI, 1.11–1.40], < 0.001). White patients had increased odds of receiving a kidney-only transplant (OR 0.48 [95% CI, 0.38–0.61], p < 0.001), and specifically increased odds of receiving a living donor kidney (OR 0.34 [0.25–0.45], p < 0.001).

Conclusion

This study found that Black patients are more likely to receive a SPKt. Results suggest that there are opportunities for additional inquiry related to patient removal from the waitlist, particularly considering White patients received or accepted more kidney-only transplants and were more likely to receive a living donor kidney-only transplant.

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非西班牙裔黑人与非西班牙裔白人胰肾同时移植候选者和受者之间的比较。
简介:本研究调查了黑人和白人患者的同步胰腺-肾脏移植(SPKt)情况:本研究调查了黑人和白人患者的胰腺-肾脏同步移植(SPKt)情况,以确定移植手术、候选天数和SPKt候选名单除名原因方面的差异:使用器官共享联合网络标准移植分析与研究档案,纳入了2009年1月1日至2021年5月31日期间的患者。采用倾向得分匹配法选出了三个队列(总体队列、仅接受 SPKt 的队列和未接受移植的队列)。条件逻辑回归用于分类结果。使用负二项回归比较了候选名单上的天数:黑人患者接受 SPKt 的几率增加(OR,1.25 [95% CI,1.11-1.40],P 结论:该研究发现,黑人患者接受 SPKt 的几率更高(OR,1.25 [95% CI,1.11-1.40],P本研究发现,黑人患者接受 SPKt 的几率更高。结果表明,有机会对患者从等待名单中删除的情况进行更多调查,特别是考虑到白人患者接受或接受了更多的纯肾移植,并且更有可能接受纯活体肾移植。
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来源期刊
Clinical Transplantation
Clinical Transplantation 医学-外科
CiteScore
3.70
自引率
4.80%
发文量
286
审稿时长
2 months
期刊介绍: Clinical Transplantation: The Journal of Clinical and Translational Research aims to serve as a channel of rapid communication for all those involved in the care of patients who require, or have had, organ or tissue transplants, including: kidney, intestine, liver, pancreas, islets, heart, heart valves, lung, bone marrow, cornea, skin, bone, and cartilage, viable or stored. Published monthly, Clinical Transplantation’s scope is focused on the complete spectrum of present transplant therapies, as well as also those that are experimental or may become possible in future. Topics include: Immunology and immunosuppression; Patient preparation; Social, ethical, and psychological issues; Complications, short- and long-term results; Artificial organs; Donation and preservation of organ and tissue; Translational studies; Advances in tissue typing; Updates on transplant pathology;. Clinical and translational studies are particularly welcome, as well as focused reviews. Full-length papers and short communications are invited. Clinical reviews are encouraged, as well as seminal papers in basic science which might lead to immediate clinical application. Prominence is regularly given to the results of cooperative surveys conducted by the organ and tissue transplant registries. Clinical Transplantation: The Journal of Clinical and Translational Research is essential reading for clinicians and researchers in the diverse field of transplantation: surgeons; clinical immunologists; cryobiologists; hematologists; gastroenterologists; hepatologists; pulmonologists; nephrologists; cardiologists; and endocrinologists. It will also be of interest to sociologists, psychologists, research workers, and to all health professionals whose combined efforts will improve the prognosis of transplant recipients.
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