Measurement of Natriuretic Peptides in Patients with Suspected Heart Failure to Prevent Overuse of Echocardiography - a Pilot Study.

IF 0.7 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY Clinical laboratory Pub Date : 2024-07-01 DOI:10.7754/Clin.Lab.2024.231110

Francois-Xavier Goudot, Marie Paugam, Nabil Bendaoud, Cedric Desbene, Mohamed B El-Sayed, Pierre-Olivier Schismanoff, Christophe Meune

{"title":"Measurement of Natriuretic Peptides in Patients with Suspected Heart Failure to Prevent Overuse of Echocardiography - a Pilot Study.","authors":"Francois-Xavier Goudot, Marie Paugam, Nabil Bendaoud, Cedric Desbene, Mohamed B El-Sayed, Pierre-Olivier Schismanoff, Christophe Meune","doi":"10.7754/Clin.Lab.2024.231110","DOIUrl":null,"url":null,"abstract":"Background: European Society of Cardiology (ESC) guidelines recommend measuring natriuretic peptides (BNP or NT-proBNP) in patients with suspected heart failure (HF) as a first-line tool. HF should be ruled-out if concen-trations of NT-proBNP are below 300 ng/L and 125 ng/L for acute HF and chronic HF, respectively.Methods: Patients with suspected HF referred for transthoracic echocardiography (TTE) were enrolled; NT-pro-BNP concentrations were obtained from medical charts (measurement < 48 hours) or prospectively measured on the day of TTE.Results: Out of 109 patients, NT-proBNP was measured by the referring department before TTE in 40 patients (36.7%), and 37.5% of these patients had NT-proBNP concentration below the rule-out threshold. NT-proBNP was measured in additional 38 patients on the day of TTE. Overall, 38.5% of the patients had a NT-proBNP concentration below the threshold value.Conclusions: Natriuretic peptides are not routinely measured in patients with suspected HF; systematic measurement would reduce unnecessary TTE by at least 38.5%.","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2024.231110","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: European Society of Cardiology (ESC) guidelines recommend measuring natriuretic peptides (BNP or NT-proBNP) in patients with suspected heart failure (HF) as a first-line tool. HF should be ruled-out if concen-trations of NT-proBNP are below 300 ng/L and 125 ng/L for acute HF and chronic HF, respectively.

Methods: Patients with suspected HF referred for transthoracic echocardiography (TTE) were enrolled; NT-pro-BNP concentrations were obtained from medical charts (measurement < 48 hours) or prospectively measured on the day of TTE.

Results: Out of 109 patients, NT-proBNP was measured by the referring department before TTE in 40 patients (36.7%), and 37.5% of these patients had NT-proBNP concentration below the rule-out threshold. NT-proBNP was measured in additional 38 patients on the day of TTE. Overall, 38.5% of the patients had a NT-proBNP concentration below the threshold value.

Conclusions: Natriuretic peptides are not routinely measured in patients with suspected HF; systematic measurement would reduce unnecessary TTE by at least 38.5%.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

测量疑似心力衰竭患者的钠尿肽以防止过度使用超声心动图--一项试点研究。

背景：欧洲心脏病学会（ESC）指南建议将测量钠尿肽（BNP 或 NT-proBNP）作为疑似心力衰竭（HF）患者的一线工具。如果急性心力衰竭和慢性心力衰竭患者的 NT-proBNP 浓度分别低于 300 纳克/升和 125 纳克/升，则应排除心力衰竭：方法：纳入转诊至经胸超声心动图（TTE）检查的疑似 HF 患者；NT-pro-BNP 浓度取自病历（测量 < 48 小时）或在 TTE 当天进行前瞻性测量：在109名患者中，40名患者（36.7%）的NT-proBNP是在TTE前由转诊部门测量的，其中37.5%患者的NT-proBNP浓度低于排除阈值。另有 38 名患者在 TTE 当天测量了 NT-proBNP。总体而言，38.5% 的患者的 NT-proBNP 浓度低于阈值：结论：对于疑似心房颤动患者，未对钠尿肽进行常规测量；系统性测量可减少至少 38.5% 不必要的 TTE。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.