Inter-observational analysis of computed tomography parameters to predict nonobvious posterior ligament complex injury in neurologically intact patients with thoracolumbar trauma

IF 1.9 Q3 CLINICAL NEUROLOGY Brain & spine Pub Date : 2024-01-01 DOI:10.1016/j.bas.2024.102855
Joana Araújo de Azevedo , Carolina Garcez Martins , Nuno Oliveira , Pedro Varanda , Bruno Direito-Santos
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Abstract

Introduction

Assessing the integrity of the posterior ligament complex (PLC), as a key element in the characterization of an unstable Thoracolumbar fracture (TLF), is challenging, but crucial in the choice of treatment.

Research question

How to create a reproducible score using combined parameters of Computed Tomography (CT) to predict nonobvious PLC injury. How CT parameters relate with PLC status.

Material and methods

Retrospective analysis of neurologically intact patients with an acute traumatic TLF, who underwent CT and Magnetic Resonance Imaging (MRI) within 72 h, in the Emergency Department of a single institution between January 2016 and 2022. Four investigators rated independently 11 parameters on CT and PLC integrity on MRI. The interrater reliability of the CT parameters was evaluated, and two risk scores were created to predict PLC injury on CT using the coefficients of the multivariate logistic regression.

Results

154 patients were included, of which 62 with PLC injury. All CT measurements had excellent or good interrater reliability. Patients with Horizontal Fracture of the lamina or pedicle (HLPF), Spinous process fracture (SPF) and Interspinous Distance Widening (IDW) were positively associated with PLC injury (p < 0.001, p < 0.001 and p = 0.045, respectively). Risk Score 2 (RS2), which included only statistically significant variables, had a total of 75.9% of correct classifications (p < 0.001), with a sensitivity of 71.0% and specificity of 78.3% to estimate PLC injury detected in the MRI.

Discussion and conclusion

Standardized procedures pre-established in the CT measurement protocol were effective. Identically to early findings, those three CT measurements showed a positive relation to PLC injury, thus enhancing the conclusions of previous studies. Comparing to the reliability of the CT findings above mentioned, the score was less precise.

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对计算机断层扫描参数进行观察间分析,以预测神经系统完好的胸腰椎创伤患者的非明显后韧带复合体损伤情况
导言评估后韧带复合体(PLC)的完整性是鉴定不稳定型胸腰椎骨折(TLF)的关键因素,具有挑战性,但对治疗方法的选择至关重要。研究问题如何使用计算机断层扫描(CT)的综合参数创建一个可重复的评分,以预测非明显的PLC损伤。材料与方法回顾性分析 2016 年 1 月至 2022 年期间在一家机构急诊科接受 CT 和磁共振成像(MRI)检查的神经功能完好的急性创伤性 TLF 患者。四名研究人员分别独立评定 CT 的 11 项参数和 MRI 的 PLC 完整性。评估了CT参数的交互可靠性,并创建了两个风险评分,利用多变量逻辑回归系数预测CT上的PLC损伤。所有的 CT 测量结果都具有极佳或良好的互测可靠性。片层或椎弓根水平骨折(HLPF)、棘突骨折(SPF)和棘间距增宽(IDW)与 PLC 损伤呈正相关(分别为 p < 0.001、p < 0.001 和 p = 0.045)。风险评分 2(RS2)仅包括具有统计学意义的变量,其正确分类率为 75.9%(p <0.001),对 MRI 检测到的 PLC 损伤的估计灵敏度为 71.0%,特异性为 78.3%。与早期研究结果相同,这三种 CT 测量结果与 PLC 损伤呈正相关,从而加强了之前研究的结论。与上述 CT 结果的可靠性相比,评分的精确度较低。
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来源期刊
Brain & spine
Brain & spine Surgery
CiteScore
1.10
自引率
0.00%
发文量
0
审稿时长
71 days
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