{"title":"Boundedness and asymptotic behavior in a quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata","authors":"Luxu Zhou, Fugeng Zeng, Lei Huang","doi":"10.1016/j.rinam.2024.100473","DOIUrl":null,"url":null,"abstract":"<div><p>This paper is concerned with a three-component quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata <span><span><span><math><mfenced><mrow><mtable><mtr><mtd><msub><mrow><mi>u</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mo>∇</mo><mfenced><mrow><msub><mrow><mi>D</mi></mrow><mrow><mn>1</mn></mrow></msub><mrow><mo>(</mo><mi>u</mi><mo>)</mo></mrow><mo>∇</mo><mi>u</mi></mrow></mfenced><mo>−</mo><msub><mrow><mi>χ</mi></mrow><mrow><mn>1</mn></mrow></msub><mo>∇</mo><mfenced><mrow><mfrac><mrow><mi>u</mi></mrow><mrow><mi>w</mi></mrow></mfrac><mo>∇</mo><mi>w</mi></mrow></mfenced><mo>+</mo><mi>w</mi><mo>−</mo><msub><mrow><mi>μ</mi></mrow><mrow><mn>1</mn></mrow></msub><msup><mrow><mi>u</mi></mrow><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mn>1</mn></mrow></msub></mrow></msup><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><msub><mrow><mi>v</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mo>∇</mo><mfenced><mrow><msub><mrow><mi>D</mi></mrow><mrow><mn>2</mn></mrow></msub><mrow><mo>(</mo><mi>v</mi><mo>)</mo></mrow><mo>∇</mo><mi>v</mi></mrow></mfenced><mo>−</mo><msub><mrow><mi>χ</mi></mrow><mrow><mn>2</mn></mrow></msub><mo>∇</mo><mfenced><mrow><mfrac><mrow><mi>v</mi></mrow><mrow><mi>w</mi></mrow></mfrac><mo>∇</mo><mi>w</mi></mrow></mfenced><mo>+</mo><mi>w</mi><mo>+</mo><mi>r</mi><mi>u</mi><mi>v</mi><mo>−</mo><msub><mrow><mi>μ</mi></mrow><mrow><mn>2</mn></mrow></msub><msup><mrow><mi>v</mi></mrow><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mn>2</mn></mrow></msub></mrow></msup><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><msub><mrow><mi>w</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mi>Δ</mi><mi>w</mi><mo>+</mo><mi>u</mi><mo>+</mo><mi>v</mi><mo>−</mo><mi>w</mi><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><mfrac><mrow><mi>∂</mi><mi>u</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mfrac><mrow><mi>∂</mi><mi>v</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mfrac><mrow><mi>∂</mi><mi>w</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mn>0</mn><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>∂</mi><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><mi>u</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>u</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mi>v</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>v</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mi>w</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>w</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mi>x</mi><mo>∈</mo><mi>Ω</mi><mo>,</mo></mtd></mtr></mtable></mrow></mfenced></math></span></span></span>associated with homogeneous Neumann boundary conditions in a convex smooth bounded domain <span><math><mrow><mi>Ω</mi><mo>⊂</mo><msup><mrow><mi>R</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span>. For <span><math><mrow><mi>i</mi><mo>=</mo><mn>1</mn><mo>,</mo><mn>2</mn><mo>,</mo></mrow></math></span> the parameters <span><math><mrow><msub><mrow><mi>χ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><msub><mrow><mi>μ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><mi>r</mi></mrow></math></span> are positive and <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>≥</mo><mn>2</mn></mrow></math></span>. The nonlinear diffusion functions <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>∈</mo><msup><mrow><mi>C</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> satisfy <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>⩾</mo><msup><mrow><mrow><mo>(</mo><mi>s</mi><mo>+</mo><mn>1</mn><mo>)</mo></mrow></mrow><mrow><msub><mrow><mi>α</mi></mrow><mrow><mi>i</mi></mrow></msub></mrow></msup></mrow></math></span> for all <span><math><mrow><mi>s</mi><mo>≥</mo><mn>0</mn></mrow></math></span>. We delve into analyzing the global existence and boundedness of classical solutions for the aforementioned system under specific conditions. Additionally, in the scenario where <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>=</mo><mn>2</mn></mrow></math></span>, we develop a Lyapunov functional and scrutinize its temporal evolution to ascertain the asymptotic stability of the coexistence state.</p></div>","PeriodicalId":36918,"journal":{"name":"Results in Applied Mathematics","volume":"23 ","pages":"Article 100473"},"PeriodicalIF":1.4000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590037424000438/pdfft?md5=1c7b136d913734673823e8437fc9fa7f&pid=1-s2.0-S2590037424000438-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Results in Applied Mathematics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590037424000438","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
This paper is concerned with a three-component quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata associated with homogeneous Neumann boundary conditions in a convex smooth bounded domain . For the parameters are positive and . The nonlinear diffusion functions satisfy for all . We delve into analyzing the global existence and boundedness of classical solutions for the aforementioned system under specific conditions. Additionally, in the scenario where , we develop a Lyapunov functional and scrutinize its temporal evolution to ascertain the asymptotic stability of the coexistence state.