Targeted Therapy Innovations for Melanoma

IF 2.5 3区 医学 Q2 HEMATOLOGY Hematology-Oncology Clinics of North America Pub Date : 2024-07-08 DOI:10.1016/j.hoc.2024.05.006
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黑色素瘤靶向治疗创新。
黑色素瘤是一种黑色素细胞恶性肿瘤,由于其侵袭性强、转移潜力大,给临床治疗带来了巨大挑战。靶向治疗的出现彻底改变了黑色素瘤的治疗格局,尤其是针对携带特定基因改变(如 BRAF V600E 突变)的肿瘤。尽管靶向药物取得了初步成功,但耐药性不可避免地产生了,这凸显了对新型治疗策略的需求。本综述探讨了黑色素瘤靶向治疗的最新进展,重点关注新的分子靶点、联合疗法和克服耐药性的策略。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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