Oscillation steers differentiation.

Kyle A LaBella, Efren A Reyes, Louis Vermeulen
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引用次数: 0

Abstract

The differentiation trajectories defining enteroendocrine (EE) cell heterogeneity remain obscure. In this issue of Cell Stem Cell, Singh et al.1 map the differentiation landscape of EE cells, identifying early oscillating cell progenitor states, which play a critical role in generating terminal EE cell diversity.

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震荡引导分化。
定义肠内分泌(EE)细胞异质性的分化轨迹仍然模糊不清。在本期《细胞干细胞》(Cell Stem Cell)杂志上,辛格等人1绘制了肠内分泌细胞的分化图谱,确定了早期振荡细胞祖细胞状态,这种状态在产生终端肠内分泌细胞多样性方面发挥着关键作用。
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