Characteristics of the radial peripapillary capillary network in patients with COVID-19 based on optical coherence tomography angiography: A literature review

IF 2.5 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Advances in medical sciences Pub Date : 2024-07-06 DOI:10.1016/j.advms.2024.07.001

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Abstract

Purpose

This review aimed to evaluate the significance of assessing radial peripheral capillary (RPC) network parameters by optical coherence tomography angiography (OCTA) in patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection confirmed by polymerase chain reaction.

Methods

A literature search was conducted in the PubMed database to select high-quality reviews and original articles on the use of OCTA for visualizing the RPC network and calculating RPC parameters.

Results

The study revealed that systemic hypoxia, hypercoagulable state, and inflammation affect the RPC network in patients with coronavirus disease 2019 (COVID-19). Reduced RPC parameters were observed early in the course of SARS-CoV-2 infection and after several months of follow-up. Additionally, there was a correlation between reduced RPC parameters and subsequent thinning of the retinal nerve fiber layer.

Conclusions

The OCTA examination of the retina and optic disc should be considered in patients with a history of COVID-19 to assess the impact of systemic hypoxia and inflammation on ocular function. Follow-up assessment of these patients is also necessary to understand the potential consequences of ischemia affecting the optic nerve, retina, and choroid.

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基于光学相干断层血管造影的 COVID-19 患者桡侧毛细血管周围网络的特征：文献综述。

目的：本综述旨在评估在聚合酶链反应证实感染严重急性呼吸系统综合征冠状病毒-2（SARS-CoV-2）的患者中通过光学相干断层血管成像（OCTA）评估径向外周毛细血管（RPC）网络参数的意义：方法：在PubMed数据库中进行文献检索，选择有关使用OCTA观察RPC网络和计算RPC参数的高质量综述和原创文章：研究发现，全身缺氧、高凝状态和炎症会影响2019年冠状病毒病（COVID-19）患者的RPC网络。在SARS-CoV-2感染初期和数月随访后，观察到RPC参数降低。此外，RPC参数降低与随后视网膜神经纤维层变薄之间存在相关性：结论：对于有 COVID-19 病史的患者，应考虑对视网膜和视盘进行 OCTA 检查，以评估全身缺氧和炎症对眼部功能的影响。还需要对这些患者进行随访评估，以了解缺血对视神经、视网膜和脉络膜的潜在影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in medical sciences 医学-医学：研究与实验

CiteScore

5.00

自引率

0.00%

发文量

审稿时长

25 days

期刊介绍： Advances in Medical Sciences is an international, peer-reviewed journal that welcomes original research articles and reviews on current advances in life sciences, preclinical and clinical medicine, and related disciplines. The Journal’s primary aim is to make every effort to contribute to progress in medical sciences. The strive is to bridge laboratory and clinical settings with cutting edge research findings and new developments. Advances in Medical Sciences publishes articles which bring novel insights into diagnostic and molecular imaging, offering essential prior knowledge for diagnosis and treatment indispensable in all areas of medical sciences. It also publishes articles on pathological sciences giving foundation knowledge on the overall study of human diseases. Through its publications Advances in Medical Sciences also stresses the importance of pharmaceutical sciences as a rapidly and ever expanding area of research on drug design, development, action and evaluation contributing significantly to a variety of scientific disciplines. The journal welcomes submissions from the following disciplines: General and internal medicine, Cancer research, Genetics, Endocrinology, Gastroenterology, Cardiology and Cardiovascular Medicine, Immunology and Allergy, Pathology and Forensic Medicine, Cell and molecular Biology, Haematology, Biochemistry, Clinical and Experimental Pathology.