Smoking Pack Years and Eustachian Tube Dysfunction.

IF 1.8 Q2 OTORHINOLARYNGOLOGY OTO Open Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI:10.1002/oto2.166
Arjun Sharma, Sam MacDowell, Nihal Punjabi, Sameer Kejriwal, Vikram Sharma, Jared C Inman
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Abstract

Objective: To determine the effect of smoking history on the risk of developing obstructive eustachian tube dysfunction (OETD).

Study design: Cross-sectional review.

Setting: National database.

Methods: Data from the National Health and Nutrition Examination Survey (1999 to present) was analyzed. OETD was defined as middle ear pressure less than -100 decapascals (daPa). Nonsmokers, current smokers, with tympanometry data were analyzed. Patients under the age of 18, with myringotomy tubes, or with a sinus problem/earache/cold in the past 24 hours were excluded. The relative risks (RRs) for developing OETD were calculated for nonsmokers versus smokers and those with greater versus less than 10, 20, and 30 pack years (py).

Results: A total of 9472 patients met inclusion criteria (54.1% female, 75.9% non-Hispanic, mean age 43, 20.3% smokers). The RR of having OETD for smokers versus nonsmokers was 1.75 [95% confidence interval, CI: 1.45-2.11]. The RR of having OETD for patients with a 10+ py was 1.97 [95% CI 1.57-2.47], 20+ py was 2.29 [95% CI 1.76-2.95], and 30 py or greater was 2.08 [95% CI 1.49-2.90].

Conclusion: In this study, smoking roughly doubled the risk of developing OETD, as represented by a single measurement of negative middle ear pressure less than -100 daPa. The definition of OETD used in this study was limited, as it did not include symptomology, and more work is needed to examine additional covariates. However, these results may guide future research to better counsel and screen patients for OETD.

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吸烟包年与咽鼓管功能障碍
研究目的确定吸烟史对咽鼓管阻塞性功能障碍(OETD)发病风险的影响:横断面回顾:环境:国家数据库:方法:分析全国健康与营养调查(1999 年至今)的数据。OETD 的定义是中耳压力低于 -100 decapascals (daPa)。分析对象包括非吸烟者、当前吸烟者以及有鼓室测量数据的患者。未满 18 岁、患有耳鸣管切除术或在过去 24 小时内有鼻窦问题/耳痛/感冒的患者被排除在外。计算了非吸烟者与吸烟者、吸烟年数大于与小于 10、20 和 30 包(py)者患 OETD 的相对风险系数(RRs):共有 9472 名患者符合纳入标准(54.1% 为女性,75.9% 为非西班牙裔,平均年龄 43 岁,20.3% 为吸烟者)。吸烟者与非吸烟者相比,患 OETD 的 RR 为 1.75 [95% 置信区间,CI:1.45-2.11]。Py超过10的患者患OETD的RR为1.97 [95% CI 1.57-2.47],Py超过20的患者患OETD的RR为2.29 [95% CI 1.76-2.95],Py超过30的患者患OETD的RR为2.08 [95% CI 1.49-2.90]:在这项研究中,吸烟会使罹患 OETD 的风险增加一倍,中耳负压小于 -100 daPa 的单次测量结果即代表了这一点。本研究中使用的 OETD 定义是有局限性的,因为它不包括症状,还需要做更多的工作来研究更多的协变量。不过,这些结果可以指导未来的研究,更好地咨询和筛查 OETD 患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
OTO Open
OTO Open Medicine-Surgery
CiteScore
2.70
自引率
0.00%
发文量
115
审稿时长
15 weeks
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