Ischaemia with no obstructive coronary arteries: a review with focus on the Asian population.

Singapore medical journal Pub Date : 2024-07-01 Epub Date: 2024-07-08 DOI:10.4103/singaporemedj.SMJ-2023-116
Rodney Yu-Hang Soh, Ting-Ting Low, Ching-Hui Sia, William Kok-Fai Kong, Tiong-Cheng Yeo, Poay-Huan Loh, Kian-Keong Poh
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Abstract

Abstract: Ischaemia with no obstructive coronary arteries (INOCA) has been a diagnostic and therapeutic challenge for decades. Several studies have demonstrated that INOCA is associated with an increased risk of death, adverse cardiovascular events, poor quality of life and high healthcare cost. Although there is increasing recognition of this entity in the Western population, in the Asian population, INOCA remains elusive and its prevalence uncertain. Despite its prognostic significance, diagnosis of INOCA is often delayed. In this review, we identified the multiple barriers to its diagnosis and management, and proposed strategies to overcome them.

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无阻塞性冠状动脉缺血:以亚洲人为重点的综述。
摘要:几十年来,无阻塞性冠状动脉缺血(INOCA)一直是诊断和治疗方面的难题。多项研究表明,无阻塞性冠状动脉缺血与死亡风险增加、不良心血管事件、生活质量低下和高昂的医疗费用有关。虽然西方人对这种疾病的认识在不断提高,但在亚洲人中,INOCA 仍然难以捉摸,其发病率也不确定。尽管 INOCA 对预后具有重要意义,但其诊断往往被延迟。在这篇综述中,我们指出了INOCA诊断和管理的多重障碍,并提出了克服这些障碍的策略。
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