Pathogenic antibodies target stromal antigens in RA

IF 29.4 1区 医学 Q1 RHEUMATOLOGY Nature Reviews Rheumatology Pub Date : 2024-07-08 DOI:10.1038/s41584-024-01141-5
Jessica McHugh
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Abstract

New findings identify HSP60 and other synovial stromal-derived autoantigens as targets for pathogenic autoantibodies, exacerbating arthritis and serving as potential biomarkers.

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致病抗体靶向 RA 的基质抗原
新研究发现,HSP60 和其他滑膜基质衍生的自身抗原是致病性自身抗体的靶标,它们会加剧关节炎并成为潜在的生物标记物。
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来源期刊
Nature Reviews Rheumatology
Nature Reviews Rheumatology 医学-风湿病学
CiteScore
29.90
自引率
0.90%
发文量
137
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.
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