Hysteroscopic Management of Symptomatic Cesarean Scar Diverticulum in Patients Undergoing Frozen-Thawed Embryo Transfer: Impact on Clinical Pregnancy Rates and Pregnancy Complications.

IF 2.5 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Reproductive Sciences Pub Date : 2025-04-01 Epub Date: 2024-07-08 DOI:10.1007/s43032-024-01642-4
Qingxian Li, Xin Zhang, Song Jiang, Wenjuan Pang, Ningxia Sun
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Abstract

This retrospective cohort study aimed to compare the clinical outcomes of patients with cesarean scar defect (CSD) undergoing frozen embryo transfer (FET) with or without hysteroscopic repair surgery. The study included 82 patients, with 48 patients in surgical group A (undergoing CSD repair) and 34 patients in surgical group B (undergoing hysteroscopic treatment for other uterine lesions). The results showed that patients in group A had a larger CSD volume and a different shape compared to group B. However, there was no significant difference in clinical pregnancy rates between the two groups. Additionally, there were no differences in miscarriage, live birth, or preterm birth rates, and no complications such as scar pregnancy or placental abnormalities were observed in either group. These findings suggest that hysteroscopic treatment of CSD in symptomatic patients undergoing FET does not increase the risk of pregnancy complications and can lead to comparable clinical pregnancy rates with asymptomatic patients. Further studies with larger sample sizes are needed to confirm these results and evaluate long-term reproductive outcomes following CSD repair.

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冷冻解冻胚胎移植患者症状性剖宫产瘢痕憩室的宫腔镜治疗:对临床妊娠率和妊娠并发症的影响。
这项回顾性队列研究旨在比较剖宫产瘢痕缺损(CSD)患者接受冷冻胚胎移植(FET)和不接受宫腔镜修复手术的临床结果。研究共纳入82名患者,其中48名患者属于手术A组(接受CSD修复手术),34名患者属于手术B组(接受宫腔镜治疗其他子宫病变)。结果显示,与 B 组相比,A 组患者的 CSD 容量更大,形状也不同。此外,两组患者的流产率、活产率和早产率均无差异,也未观察到疤痕妊娠或胎盘异常等并发症。这些研究结果表明,对接受FET的无症状患者进行宫腔镜治疗CSD并不会增加妊娠并发症的风险,其临床妊娠率与无症状患者相当。要确认这些结果并评估CSD修复术后的长期生育结果,还需要进行样本量更大的进一步研究。
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来源期刊
Reproductive Sciences
Reproductive Sciences 医学-妇产科学
CiteScore
5.50
自引率
3.40%
发文量
322
审稿时长
4-8 weeks
期刊介绍: Reproductive Sciences (RS) is a peer-reviewed, monthly journal publishing original research and reviews in obstetrics and gynecology. RS is multi-disciplinary and includes research in basic reproductive biology and medicine, maternal-fetal medicine, obstetrics, gynecology, reproductive endocrinology, urogynecology, fertility/infertility, embryology, gynecologic/reproductive oncology, developmental biology, stem cell research, molecular/cellular biology and other related fields.
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