[Factors associated with left ventricular diastolic dysfunction in adults from a region of the Andes in Peru].

Aníbal V Díaz-Lazo, Mely Ruiz-Aquino, Hugo Arroyo-Hernández
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Abstract

Objective: To determine the factors associated with left ventricular diastolic dysfunction (LVDD) in adults residing in a region of the Andes in Peru.

Method: A case-control study was conducted on adults living at an altitude of more than 3000 meters in Peru. Cases consisted of patients diagnosed with LVDD through echocardiography, whereas controls were adults without LVDD, as confirmed by echocardiography.

Results: A total of 50 cases and 100 controls were included in the study. Among them, 38.7% had high blood pressure, and 41.3% were overweight. Upon adjusted analysis, age 60 or older (aOR: 4.06; 95%CI: 1.29-12.8), female sex (aOR: 2.24; 95%CI: 1.01-4.96) and left ventricular hypertrophy (aOR: 3.17; 95%CI: 1.41-7.17) were identified as statistically significant factors associated with LVDD.

Conclusions: The risk of LVDD is associated with older adults, female gender, and left ventricular hypertrophy among individuals residing above 3000 meters altitude in a region of the Andes, in Peru.

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[秘鲁安第斯地区成年人左心室舒张功能障碍的相关因素]。
目的:确定秘鲁安第斯地区成年人左心室舒张功能障碍(LVDD)的相关因素:确定秘鲁安第斯山脉地区成年人左心室舒张功能障碍(LVDD)的相关因素:对居住在秘鲁海拔 3000 米以上地区的成年人进行了一项病例对照研究。病例包括通过超声心动图确诊的低密度心血管病患者,而对照组则是通过超声心动图确诊的无低密度心血管病的成年人:研究共纳入了 50 例病例和 100 例对照。其中,38.7%的人患有高血压,41.3%的人超重。经调整分析,60 岁或以上(aOR:4.06;95%CI:1.29-12.8)、女性(aOR:2.24;95%CI:1.01-4.96)和左心室肥厚(aOR:3.17;95%CI:1.41-7.17)被确定为与 LVDD 相关的显著统计学因素:结论:在秘鲁安第斯山脉海拔 3000 米以上地区居住的人中,罹患 LVDD 的风险与老年人、女性和左心室肥大有关。
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