Influence of neonatal steroid (diethylstilbestrol, allylestrenol) treatment on the sexual behaviour of the adult rat.

Medical biology Pub Date : 1986-01-01
G Csaba, O Dobozy, J Dalló
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Abstract

A single neonatal treatment with diethylstilbestrol (DES) or allylestrenol (AE) considerably depressed the sexual activity of male rats in adulthood. DES had a stronger depressive effect than AE. Though the adult sexual activity of intact female rats was also reduced by DES it was not influenced by AE. Ovariectomized females that had been hormone-treated before experimental mating showed reduced sexual activity under the influence of neonatal DES-treatment but increased sexual activity when treated neonatally with AE.

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新生儿类固醇(己烯雌酚、烯丙烯雌醇)治疗对成年大鼠性行为的影响。
新生儿单次使用己烯雌酚(DES)或烯丙雌醇(AE)可显著抑制成年雄性大鼠的性活动。DES的抑制作用强于AE。虽然DES也能降低雌性大鼠成年后的性活动,但AE对其没有影响。在实验交配前接受激素治疗的去卵巢雌性在新生儿des治疗的影响下性活动减少,而在新生儿AE治疗下性活动增加。
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