Lithium in Drinking Water and its Potential Impact on Mental Health: A Review.

IF 3.5 4区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Current medicinal chemistry Pub Date : 2024-07-10 DOI:10.2174/0109298673315171240702103413
Geir Bjørklund, Olha Storchylo
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Abstract

This review explores the relationship between lithium in drinking water and mental health, a subject that has garnered increasing attention in investigations. Lithium, a metal with a well-established role in psychiatric medications, is found in trace amounts in drinking water, and studies suggest its potential correlations with lower rates of suicide and certain psychiatric disorders. However, these correlations do not imply causation, necessitating an examination of the underlying mechanisms. Lithium concentrations in drinking water vary globally, presenting challenges in establishing a universal threshold for "high" or "low" levels. Additionally, the optimal dosage for potential mental health benefits remains uncertain. Lithium is not considered an essential nutrient, and supplementation should be approached with caution due to possible toxicity risks, emphasizing the importance of medical supervision. The lack of causation and ongoing need for further investigation underscores the importance of cautious interpretation and transparent communication in navigating this evolving field.

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饮用水中的锂及其对心理健康的潜在影响:综述。
这篇综述探讨了饮用水中的锂与精神健康之间的关系,这是一个在调查中日益受到关注的问题。锂是一种在精神科药物中具有公认作用的金属,在饮用水中的含量微乎其微,研究表明锂与降低自杀率和某些精神障碍有潜在的相关性。然而,这些相关性并不意味着因果关系,因此有必要对其潜在机制进行研究。全球饮用水中的锂浓度各不相同,这给确定 "高 "或 "低 "水平的通用阈值带来了挑战。此外,对精神健康有潜在益处的最佳剂量仍不确定。锂不被认为是人体必需的营养素,由于可能存在毒性风险,因此应谨慎补充,并强调医疗监督的重要性。由于缺乏因果关系,且仍需进一步调查,因此在这一不断发展的领域中,谨慎解读和透明沟通显得尤为重要。
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来源期刊
Current medicinal chemistry
Current medicinal chemistry 医学-生化与分子生物学
CiteScore
8.60
自引率
2.40%
发文量
468
审稿时长
3 months
期刊介绍: Aims & Scope Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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