{"title":"Factors Associated With Unfavorable Treatment Outcomes Among Persons With Pulmonary Tuberculosis: A Multicentric Prospective Cohort Study From India.","authors":"Senbagavalli Prakash Babu, Komala Ezhumalai, Kalaivani Raghupathy, Meagan Karoly, Palanivel Chinnakali, Nikhil Gupte, Mandar Paradkar, Arutselvi Devarajan, Mythili Dhanasekaran, Kannan Thiruvengadam, Madolyn Rose Dauphinais, Akshay N Gupte, Shrivijay Balayogendra Shivakumar, Balamugesh Thangakunam, Devasahayam Jesudas Christopher, Vijay Viswanathan, Vidya Mave, Sanjay Gaikwad, Aarti Kinikar, Hardy Kornfeld, C Robert Horsburgh, Padmapriyadarsini Chandrasekaran, Natasha S Hochberg, Padmini Salgame, Amita Gupta, Gautam Roy, Jerrold Ellner, Pranay Sinha, Sonali Sarkar","doi":"10.1093/cid/ciae367","DOIUrl":null,"url":null,"abstract":"<p><p>In this prospective cohort of 2006 individuals with drug-susceptible tuberculosis in India, 18% had unfavorable treatment outcomes (4.7% treatment failure, 2.5% recurrent infection, 4.1% death, 6.8% loss to follow-up) over a median 12-month follow-up period. Age, male sex, low education, nutritional status, and alcohol use were predictors of unfavorable outcomes.</p>","PeriodicalId":10463,"journal":{"name":"Clinical Infectious Diseases","volume":" ","pages":"1034-1038"},"PeriodicalIF":8.2000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11478802/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/cid/ciae367","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In this prospective cohort of 2006 individuals with drug-susceptible tuberculosis in India, 18% had unfavorable treatment outcomes (4.7% treatment failure, 2.5% recurrent infection, 4.1% death, 6.8% loss to follow-up) over a median 12-month follow-up period. Age, male sex, low education, nutritional status, and alcohol use were predictors of unfavorable outcomes.
期刊介绍:
Clinical Infectious Diseases (CID) is dedicated to publishing original research, reviews, guidelines, and perspectives with the potential to reshape clinical practice, providing clinicians with valuable insights for patient care. CID comprehensively addresses the clinical presentation, diagnosis, treatment, and prevention of a wide spectrum of infectious diseases. The journal places a high priority on the assessment of current and innovative treatments, microbiology, immunology, and policies, ensuring relevance to patient care in its commitment to advancing the field of infectious diseases.