Combined CO2 Laser Vaporization and Bleomycin Injection to Treat Huge Adult Laryngeal Vascular Anomalies: Innovative Application of CO2 Laser in Otolaryngology

Abstract

Objectives

The aim of this study was to assess the value of CO₂ laser vaporization in treating huge adult laryngeal vascular anomalies (HALVAs) by combining it with bleomycin injection.

Materials and Methods

This study retrospectively reviewed the records of 13 adult patients who underwent 18 different procedures. Methods to treat HALVAs include traditional bleomycin injection and CO₂ laser vaporization combined with bleomycin injection between September 2009 and January 2023. Treatment results were evaluated by the grade of lumen constriction.

Results

A total of five males and eight females, with an average age of 46.3 years (range, 22–66 years), were included in the study. The huge adult laryngeal vascular anomalies in our study were greater than 1633.71 mm³, and the long diameters of the bases were longer than 15 mm. Compared with the bleomycin injection-only group, the results with the CO₂ laser vaporization and bleomycin injection combined were better.

Conclusions

Both bleomycin injection and CO₂ laser vaporization are safe treatment methods. Their combination may produce better results for huge adult laryngeal vascular anomalies.