{"title":"Orthopedic Research Funding: Assessing the Relationship between Investments and Breakthroughs.","authors":"Wazzan Aljuhani, Yakub Sayyad","doi":"10.52965/001c.120368","DOIUrl":null,"url":null,"abstract":"<p><p>Orthopedic research plays a crucial role in improving patient outcomes for musculoskeletal disorders. This narrative review explores the intricate interplay between funding patterns and the trajectory of breakthroughs achieved in this dynamic field. A meticulous search strategy identified studies illuminating the diverse sources of orthopedic research funding, including public funding (government agencies), philanthropic organizations, private sector investment, and international funding bodies. The review further delved into the spectrum of breakthroughs, encompassing fundamental scientific discoveries, technological advancements, and personalized medicine approaches. Public funding emerged as a significant pillar, supporting foundational research that lays the groundwork for future advancements. Philanthropic organizations addressed specific musculoskeletal disorders, often focusing on patient-centric applications. International funding bodies played a role in supporting research in low- and middle-income countries. Breakthroughs extended beyond cutting-edge prosthetics and minimally invasive surgeries, encompassing fundamental discoveries in areas like gene therapy and biomaterials science. Technological advancements included brain-computer interface prosthetics and 3D-printed implants. Personalized medicine offered the potential for tailored treatments based on individual needs and genetic profiles. This review underscores the complex interplay between funding patterns and breakthroughs in orthopedic research. A multifaceted approach is essential for continued progress. Fostering collaboration, optimizing funding models, and prioritizing both foundational and translational research hold the key to unlocking the true potential of orthopedic research and transforming the lives of patients suffering from musculoskeletal disorders.</p>","PeriodicalId":19669,"journal":{"name":"Orthopedic Reviews","volume":"16 ","pages":"120368"},"PeriodicalIF":1.4000,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236838/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Orthopedic Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52965/001c.120368","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Orthopedic research plays a crucial role in improving patient outcomes for musculoskeletal disorders. This narrative review explores the intricate interplay between funding patterns and the trajectory of breakthroughs achieved in this dynamic field. A meticulous search strategy identified studies illuminating the diverse sources of orthopedic research funding, including public funding (government agencies), philanthropic organizations, private sector investment, and international funding bodies. The review further delved into the spectrum of breakthroughs, encompassing fundamental scientific discoveries, technological advancements, and personalized medicine approaches. Public funding emerged as a significant pillar, supporting foundational research that lays the groundwork for future advancements. Philanthropic organizations addressed specific musculoskeletal disorders, often focusing on patient-centric applications. International funding bodies played a role in supporting research in low- and middle-income countries. Breakthroughs extended beyond cutting-edge prosthetics and minimally invasive surgeries, encompassing fundamental discoveries in areas like gene therapy and biomaterials science. Technological advancements included brain-computer interface prosthetics and 3D-printed implants. Personalized medicine offered the potential for tailored treatments based on individual needs and genetic profiles. This review underscores the complex interplay between funding patterns and breakthroughs in orthopedic research. A multifaceted approach is essential for continued progress. Fostering collaboration, optimizing funding models, and prioritizing both foundational and translational research hold the key to unlocking the true potential of orthopedic research and transforming the lives of patients suffering from musculoskeletal disorders.
骨科研究在改善肌肉骨骼疾病患者的治疗效果方面发挥着至关重要的作用。这篇叙述性综述探讨了资助模式与这一动态领域取得突破性进展之间错综复杂的相互作用。通过缜密的搜索策略,我们发现了揭示骨科研究资金来源多样性的研究,包括公共资金(政府机构)、慈善组织、私营部门投资和国际资助机构。审查进一步深入研究了各种突破,包括基础科学发现、技术进步和个性化医疗方法。公共资金是一个重要支柱,它支持为未来进步奠定基础的基础性研究。慈善组织针对特定的肌肉骨骼疾病,通常侧重于以患者为中心的应用。国际资助机构在支持中低收入国家的研究方面发挥了作用。突破不仅限于尖端假肢和微创手术,还包括基因治疗和生物材料科学等领域的基础性发现。技术进步包括脑机接口假肢和 3D 打印植入物。个性化医疗为根据个人需求和遗传特征量身定制治疗方案提供了可能。本综述强调了骨科研究中的资助模式与突破之间复杂的相互作用。要想继续取得进展,必须采取多方面的方法。促进合作、优化资助模式、优先考虑基础研究和转化研究是释放骨科研究真正潜力和改变肌肉骨骼疾病患者生活的关键。
期刊介绍:
Orthopedic Reviews is an Open Access, online-only, peer-reviewed journal that considers articles concerned with any aspect of orthopedics, as well as diagnosis and treatment, trauma, surgical procedures, arthroscopy, sports medicine, rehabilitation, pediatric and geriatric orthopedics. All bone-related molecular and cell biology, genetics, pathophysiology and epidemiology papers are also welcome. The journal publishes original articles, brief reports, reviews and case reports of general interest.