Effects of Peroperative Cold Ischemia Time and Anhepatic Phase in Adult Living Donor Liver Transplant Recipients: Operation Time That is Not Affected by the Anhepatic Phase But is Prolonged by Cold Ischemia Time

IF 0.8 4区 医学 Q4 IMMUNOLOGY Transplantation proceedings Pub Date : 2024-07-01 DOI:10.1016/j.transproceed.2024.02.029
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引用次数: 0

Abstract

Objective

It was aimed to examine the overall role of cold ischemia time and anhepatic phase durations in terms of peroperative blood transfusion needs, hospital stay conditions and postoperative charges, and survival in recipients.

Material and Methods

One hundred forty-eight adult living donor liver transplant recipients (18 years and older) were included in the study. Whether the anhepatic phase and cold ischemia duration have an effect on the rates of surgery time, blood product transfusion, total hospital and intensive care unit stay, postoperative biliary complications, hepatic vein thrombosis, portal vein thrombosis, early postoperative bleeding, sepsis, and primary graft dysfunction. Was analyzed statistically. In addition, the effect of the anhepatic phase and cold ischemia time on graft survival was statistically examined by creating an average of the patient follow-up period.

Results

It was observed that the operation time increased statistically as the cold ischemia time increased (P = .000). No statistically significant relationship was found between other findings and cold ischemia time and anhepatic phase.

Conclusion

Prolonged surgery time due to increased cold ischemia time may be an important finding in terms of peroperative and postoperative results of the graft.

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成人活体肝移植受者围手术期冷缺血时间和肝阶段的影响:手术时间不受肝脏阶段影响,但受冷缺血时间影响而延长。
目的旨在研究冷缺血时间和无肝期持续时间在受者围手术期输血需求、住院条件和术后费用以及存活率方面的总体作用:研究纳入了 148 名成年活体肝移植受者(18 岁及以上)。无肝期和冷缺血时间是否对手术时间、输血产品、总住院时间和重症监护室住院时间、术后胆道并发症、肝静脉血栓、门静脉血栓、术后早期出血、败血症和原发性移植物功能障碍的发生率有影响。进行了统计分析。此外,通过建立患者随访期的平均值,对无肝期和冷缺血时间对移植物存活率的影响进行了统计:结果:据统计,随着冷缺血时间的延长,手术时间也随之延长(P = .000)。其他结果与冷缺血时间和无肝期之间没有统计学意义上的关系:结论:冷缺血时间延长导致手术时间延长可能是影响移植物围手术期和术后效果的一个重要因素。
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来源期刊
Transplantation proceedings
Transplantation proceedings 医学-免疫学
CiteScore
1.70
自引率
0.00%
发文量
502
审稿时长
60 days
期刊介绍: Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.
期刊最新文献
Editorial Board Contents Author Index Advancing Cardiac Care: A Registry of Heart Transplantation in Latin America (1968-2022) Assessing Frailty, Rational Use of Medications, and Adherence to Immunosuppressive Therapy in Liver Transplant Recipients
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