Thymic Squamous Cell Carcinoma and Brain Metastases: Case Report and Literature Review

Mariana Agudelo-Arrieta , María Isabel Ocampo-Navia , María Carolina Martínez , María Paula Rodríguez , Isabella Lacouture , Luis Fernando Jaramillo , Eugenio Meek , Oscar Feo-Lee
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Abstract

Thymic squamous cell carcinoma (TSCC) is a rare cancer that is typically characterized by low rates of brain metastases. However, when it does occur, brain metastases of TSCC can have significant clinical implications due to its rarity and lack of established management guidelines. In this literature review and case report, we explore the clinical presentation, management, and outcomes of patients with brain metastases of TSCC.

Our literature review found that brain metastases of TSCC are relatively rare, with an estimated incidence of 5-10 % among patients with advanced-stage disease. Management of brain metastases of TSCC often involves a combination of surgical resection, radiation therapy, and chemotherapy. However, due to the rarity of this condition, there is currently limited evidence to guide optimal treatment strategies.

We also present a case report of a patient with TSCC who was presented with a brain metastasis. This case highlights the importance of early diagnosis and prompt management of brain metastasis of TSCC to improve patient outcomes. Our review and case report underscore the need for further research to improve our understanding of the clinical characteristics, optimal management, and prognosis of patients with brain metastasis of TSCC.

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胸腺鳞状细胞癌与脑转移:病例报告和文献综述
胸腺鳞状细胞癌(TSCC)是一种罕见的癌症,其典型特征是脑转移率较低。然而,由于其罕见性和缺乏既定的管理指南,TSCC 的脑转移一旦发生,就会对临床产生重大影响。在这篇文献综述和病例报告中,我们探讨了TSCC脑转移患者的临床表现、管理和预后。我们的文献综述发现,TSCC脑转移相对罕见,估计晚期患者的发病率为5-10%。TSCC脑转移的治疗通常包括手术切除、放疗和化疗。然而,由于这种疾病的罕见性,目前指导最佳治疗策略的证据有限。我们还报告了一例出现脑转移的 TSCC 患者的病例。本病例强调了早期诊断和及时处理 TSCC 脑转移对改善患者预后的重要性。我们的综述和病例报告强调了进一步研究的必要性,以提高我们对TSCC脑转移患者的临床特征、最佳治疗和预后的认识。
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来源期刊
Brain disorders (Amsterdam, Netherlands)
Brain disorders (Amsterdam, Netherlands) Neurology, Clinical Neurology
CiteScore
1.90
自引率
0.00%
发文量
0
审稿时长
51 days
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