Gene-Environment Interactions and Gene–Gene Interactions on Two Biological Age Measures: Evidence from Taiwan Biobank Participants (Adv. Biology 7/2024)
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Abstract
Gene-Environment Interactions
Gene-environment interactions on PhenoAgeAccel (age-adjusted PhenoAge) were searched through variance quantitative trait loci (vQTLs) analyses of 111,996 Taiwan Biobank participants. A total of 4 nearly independent vQTLs were identified with p < 5E-8. Further studies showed that smoking exacerbated the vQTLs' aging effects, while higher educational attainment attenuated these effects. More details can be found in article number 2400149 by Wan-Yu Lin.
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