Peptides and Wound Healing: From Monomer to Combination

Abstract

Peptides are a kind of compounds formed by α-amino acids linked together by peptide bonds, which are also intermediate products of protein hydrolysis. Nowadays, they mostly come form laboratory chemical synthesis and protein degradation. Peptides are important in maintaining the normal functioning of our bodies, involved in many aspects such as nerve, homeostasis, growth and development and healing, as well as wound repair. When human skin is exposed to external mechanical, physical and chemical stimuli, it forms wounds. When the body or wound environment is in a special state (hyperglycemia, infection, etc.), the process of wound healing will be limited or even non-healing. In this review, we will introduce the peptides which can promote wound healing and describe their function after partial tissue damage in the field of sports system. In addition, we introduce peptides combined with modern tissue engineering, material science and 3D technology, which can exploit the advantages of peptides and overcome their disadvantages. Finally, we discuss the current development status and prospects of the field of peptides.