The value of susceptibility weighted imaging for immediate assessing the hyperacute outcome of MRgFUS ablation for uterine fibroids: a preliminary study.

IF 3 3区 医学 Q2 ONCOLOGY International Journal of Hyperthermia Pub Date : 2024-01-01 Epub Date: 2024-07-14 DOI:10.1080/02656736.2024.2377346
Yaoqu Huang, Shouguo Zhou, Yinghua Su, Zhuochao Pang, Shihua Cai
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Abstract

Purpose: To investigate the value of susceptibility weighted imaging (SWI) for assessing the hyperacute outcome of ablation of uterine fibroids immediately after magnetic resonance-guided focused ultrasound (MRgFUS) treatment.

Methods: This retrospective imaging study included patients who underwent SWI and contrast-enhanced (CE) MR within 15 min of MRgFUS ablation for uterine fibroids. Two readers independently assessed the SWI features of ablative lesions and their association with the non-perfused volume (NPV) ratio. The intraclass correlation coefficient (ICC) and diagnostic value of SWI findings were calculated.

Results: A total of 27 uterine fibroids from 21 participants (mean age 40.1 ± 7.2 years) were analyzed. 51.9% (14/27) leiomyomas had NPV ratio ≥90%. In post-ablation SWI images, the interobserver ICC for the relative signal intensity and hypointense peripheral rim were 0.613 and 0.843, respectively (both p < .001). There was a significant difference in the prevalence of hypointense peripheral rim in leiomyomas with NPV ratio ≥90% and < 90% (p < .01), while the prevalence of relative signal intensity showed no significant difference (p > .05). When using the complete hypointense peripheral rim as a diagnostic criterion to identify NPV ratio ≥ 90%, readers 1 and 2 showed diagnostic sensitivity, specificity, and accuracy of 85.7%, 76.9%, 81.5%, and 78.6%, 76.9%, 77.8%, respectively.

Conclusion: Identifying a complete hypointense peripheral rim on SWI may be a potential imaging marker for assessing the hyperacute outcome of uterine fibroids ablation by MRgFUS, specifically in determining whether the NPV ratio is ≥90%.

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易感加权成像对即时评估 MRgFUS 子宫肌瘤消融术超急性结果的价值:一项初步研究。
目的:研究磁共振引导下聚焦超声(MRgFUS)治疗后立即进行的感性加权成像(SWI)对评估子宫肌瘤消融术超急性结果的价值:这项回顾性成像研究纳入了在MRgFUS消融治疗子宫肌瘤后15分钟内接受SWI和造影剂增强(CE)MR检查的患者。两名阅读者独立评估了消融病灶的 SWI 特征及其与非灌注容积 (NPV) 比值的关系。计算了SWI结果的类内相关系数(ICC)和诊断价值:结果:共分析了 21 名参与者(平均年龄为 40.1 ± 7.2 岁)的 27 个子宫肌瘤。51.9%(14/27)的子宫肌瘤NPV比值≥90%。在消融后的 SWI 图像中,相对信号强度和低密度周边边缘的观察者间 ICC 分别为 0.613 和 0.843(均 p p > .05)。当使用完整的低密度外周缘作为诊断标准以确定 NPV 比率≥ 90% 时,读者 1 和读者 2 的诊断敏感性、特异性和准确性分别为 85.7%、76.9%、81.5% 和 78.6%、76.9%、77.8%:在SWI上识别完整的低密度外周边缘可能是评估MRgFUS子宫肌瘤消融术超急性结果的潜在成像标志,特别是在确定NPV比值是否≥90%时。
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来源期刊
CiteScore
5.90
自引率
12.90%
发文量
153
审稿时长
6-12 weeks
期刊介绍: The International Journal of Hyperthermia
期刊最新文献
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