Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes.

IF 2.1 4区 医学 Q2 SURGERY Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-07-14 DOI:10.1080/08941939.2024.2376548
Maria Luiza Gandra de Meira, Renata Buraschi Antunes, Vitoria de Oliveira Zani, Gustavo Dutra de Oliveira, Diego Generoso, Erika Veruska Paiva Ortolan, Pedro Luiz Toledo de Arruda Lourenção
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Abstract

As far as we know, no report uses the Swenson transanal endorectal pull-through technique in an animal model. Our objective is to describe the use of this technique as an experimental model for training and research purposes. Ten Norfolk hybrid rabbits were randomly selected from our experimental laboratory, with a mean weight of 3539.3 (± 678.4) g. Neither colon preparation nor fast were used before the procedures. The surgical technique was based on the description performed by Levitt et al. (2013, J Pediatr Surg. 2013;48(11):2289-2295). Information related to the surgical procedures and the clinical evolution in the postoperative period were recorded and analyzed. There were no deaths or severe complications. The anesthetic and the surgical times were significantly higher for the first three animals of the experiment. Our animal model proved adequate to perform the transanal endorectal Swenson pull-through technique, allowing the training of surgical skills through a model similar to the human, with few anesthetic complications and good postoperative evolution, including postoperative follow-up. We believe that it will serve as a learning tool in many institutions that are continuously searching for improved new techniques and will support new researches in this area.

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开发 Swenson 经肛门直肠内拉穿动物模型:为培训和研究提供新的可能性。
据我们所知,还没有在动物模型中使用 Swenson 经肛门直肠内拉穿技术的报道。我们的目的是描述该技术作为实验模型在训练和研究中的应用。从我们的实验实验室随机挑选了 10 只诺福克杂交兔,平均体重为 3539.3 (± 678.4) 克。手术技术基于 Levitt 等人的描述(2013 年,J Pediatr Surg. 2013;48(11):2289-2295)。记录并分析了手术过程和术后临床演变的相关信息。无死亡病例或严重并发症。实验中前三只动物的麻醉时间和手术时间明显较长。事实证明,我们的动物模型足以进行经肛门直肠Swenson拉通技术,可以通过与人类相似的模型训练手术技能,麻醉并发症少,术后演变良好,包括术后随访。我们相信,它将成为许多不断探索改进新技术的机构的学习工具,并将为该领域的新研究提供支持。
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来源期刊
CiteScore
4.20
自引率
0.00%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Journal of Investigative Surgery publishes peer-reviewed scientific articles for the advancement of surgery, to the ultimate benefit of patient care and rehabilitation. It is the only journal that encompasses the individual and collaborative efforts of scientists in human and veterinary medicine, dentistry, basic and applied sciences, engineering, and law and ethics. The journal is dedicated to the publication of outstanding articles of interest to the surgical research community.
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