Elevated Mood Induced by Subthalamic Nucleus Deep Brain Stimulation: A Video-Recorded Case Report.

IF 2.1 Q2 CLINICAL NEUROLOGY Tremor and Other Hyperkinetic Movements Pub Date : 2024-07-12 eCollection Date: 2024-01-01 DOI:10.5334/tohm.900
Patricia B Coutinho, Kara A Johnson, Andreea L Seritan, Nicholas B Galifianakis, Robert Coleman, Doris Wang, Caroline A Racine, Jill L Ostrem, Philip A Starr, Coralie de Hemptinne
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Abstract

Background: Deep brain stimulation (DBS) can be an effective therapy to control motor signs in patients with Parkinson's disease (PD). However, subthalamic nucleus (STN) DBS can induce undesirable psychiatric adverse effects, including elevated mood.

Case report: We reported a video case of a 73-year-old male implanted with bilateral STN DBS who experienced stimulation-induced elevated mood. A correlation between mood changes and enhanced activation of the ventromedial region in the left STN was observed.

Discussion: This video case report illustrates STN DBS-induced elevated mood and enhances early symptom recognition for patients and diagnostic awareness for professionals.

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眼下核深部脑刺激引起的情绪高涨:录像病例报告
背景:脑深部刺激(DBS)是控制帕金森病(PD)患者运动症状的有效疗法。然而,丘脑下核(STN)DBS 可诱发不良的精神不良反应,包括情绪高涨:我们报告了一例植入双侧 STN DBS 的 73 岁男性患者的视频病例,该患者经历了刺激引起的情绪高涨。我们观察到情绪变化与左侧 STN 腹内侧区域激活增强之间存在相关性:本视频病例报告说明了 STN DBS 引起的情绪高涨,提高了患者的早期症状识别能力和专业人员的诊断意识。
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来源期刊
CiteScore
4.00
自引率
4.50%
发文量
31
审稿时长
6 weeks
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