The nosocomial infection survey among patients suffering from the Coronavirus disease-2019 hospitalized in Ayatollah Rouhani Hospital, Babol.

Pub Date : 2024-01-01 DOI:10.22088/cjim.15.3.509

Masomeh Bayani, Samaneh Rouhi, Rouzbeh Mohammadi Abandansari, Farzane Jafarian, Zahra Ahmadnia, Hossein Ghorbani, Alireza Firouzjahi, Mohammad Ranaee, Somayeh Ahmadi Goorji

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Abstract

Background: Having a weakened immune system can make patients easily get nosocomial infection (NI) with multi-drug resistant (MDR) bacteria and put them in a dangerous situation. It causes long hospital stays, disability, economic burden, and even death. The present study aimed to determine the prevalence of NI in patients suffering from COVID-19.

Methods: In this retrospective study, the information on 250 patients suffering from COVID-19 in the intensive care unit (ICU) (2020 to 2021) was considered. For statistical analysis, analysis of variance (ANOVA), paired samples t-test, and chi-square using SPSS-23 software were used (p<0.05).

Results: Two hundred and fifty hospitalized (107 females and 143 males, mean ± standard deviation (SD) of age; 56.50 ± 17.20) patients were considered. The most (97.60%) medicine prescribed was remdesivir. Candida spp. (two females), Escherichia coli (two females), Acinetobacter spp. (one female), Citrobacter spp. (one female), Pseudomonas spp. (one male), Sphingomonas spp. (one male), Stenotrophomonas spp. (one male) and Enterobacter spp. (one male) were isolated from the patient's specimens. Four of seven bacterial isolates were positive for MDR. NI was diagnosed in six patients. There was no significant relationship between the age with the isolated microbes (P=0.154) and MDR (P=0.987) and also between gender with common microbes (P=0.576) and MDR (P=0.143).

Conclusion: The coexistence of bacteria and NI was observed in patients. Remdesivir was prescribed for most patients. Most bacteria were resistant to antibiotics, especially, β-lactams.

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在巴博勒阿亚图拉-鲁哈尼医院住院的冠状病毒病-2019 患者中进行的院内感染调查。

背景：免疫力低下的病人很容易感染多重耐药菌（MDR），从而陷入危险境地。它会导致长期住院、残疾、经济负担甚至死亡。本研究旨在确定 COVID-19 患者的 NI 感染率：在这项回顾性研究中，考虑了重症监护室（ICU）中 250 名 COVID-19 患者的信息（2020 年至 2021 年）。统计分析采用SPSS-23软件进行方差分析（ANOVA）、配对样本t检验和卡方检验（PResults：250 名住院患者（107 名女性和 143 名男性，平均年龄（56.50±17.20）岁，标准差（SD）。处方最多（97.60%）的药物是雷米替韦。从患者标本中分离出念珠菌属（女性 2 例）、大肠埃希菌属（女性 2 例）、醋杆菌属（女性 1 例）、枸橼酸杆菌属（女性 1 例）、假单胞菌属（男性 1 例）、鞘氨醇单胞菌属（男性 1 例）、臭单胞菌属（男性 1 例）和肠杆菌属（男性 1 例）。七种细菌分离物中有四种呈 MDR 阳性。六名患者确诊为 NI。年龄与分离出的微生物（P=0.154）和 MDR（P=0.987）之间无明显关系，性别与常见微生物（P=0.576）和 MDR（P=0.143）之间也无明显关系：结论：在患者中观察到细菌和NI共存。结论：在患者中观察到细菌和 NI 同时存在。大多数细菌对抗生素，尤其是β-内酰胺类抗生素具有耐药性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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