Harmonization of the Upfront Osteosarcoma Treatment Paradigm for Adolescents and Young Adults.

IF 1.2 4区 医学 Q4 ONCOLOGY Journal of adolescent and young adult oncology Pub Date : 2024-07-15 DOI:10.1089/jayao.2024.0054
Nicole P Daukshus, Viswatej Avutu, Emily Long Sarro, Michael D Kinnaman, Emily K Slotkin, Katherine Thornton, Mark A Dickson, Nancy T Sklarin, William D Tap, Julia Glade Bender
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Abstract

Limited guidance exists on streamlining cancer therapy for adolescent and young adult (AYA) patients 15-39 years of age, as much of the current data are extrapolated from pediatric or adult counterparts and can differ significantly between the two care models. Harmonization of standard treatment approaches has the potential to improve outcomes and establish a foundation for the development of future clinical trials. We present our experience harmonizing treatment and supportive care regimens for AYA patients with osteosarcoma receiving treatment with methotrexate, doxorubicin, and cisplatin (MAP) therapy on the pediatric and adult sarcoma services at the Memorial Sloan Kettering Cancer Center.

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统一青少年骨肉瘤前期治疗范例。
目前,针对 15-39 岁青少年和年轻成人(AYA)患者简化癌症治疗的指导非常有限,因为目前的大部分数据都是从儿科或成人患者中推断出来的,这两种治疗模式之间可能存在很大差异。统一标准治疗方法有可能改善治疗效果,并为未来临床试验的发展奠定基础。我们介绍了纪念斯隆-凯特琳癌症中心(Memorial Sloan Kettering Cancer Center)的儿童和成人肉瘤服务部门在协调接受甲氨蝶呤、多柔比星和顺铂(MAP)治疗的青少年骨肉瘤患者的治疗和支持治疗方案方面的经验。
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来源期刊
CiteScore
3.70
自引率
15.00%
发文量
114
期刊介绍: Journal of Adolescent and Young Adult Oncology (JAYAO) breaks new ground as the first cancer journal dedicated to all aspects of adolescent and young adult (AYA)-aged cancer patients and survivors. JAYAO is the only central forum for peer-reviewed articles, reviews, and research in the field, bringing together all AYA oncology stakeholders and professionals across disciplines, including clinicians, researchers, psychosocial and supportive care providers, and pediatric and adult cancer institutions.
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