CGRP Modulating Therapies: An Update.

IF 5.4 3区 材料科学 Q2 CHEMISTRY, PHYSICAL ACS Applied Energy Materials Pub Date : 2024-09-01 Epub Date: 2024-07-17 DOI:10.1007/s11910-024-01363-w
Kate Bedrin, Tulsi Shah, Shivani Vaidya, Jessica Ailani
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Abstract

Introduction: Calcitonin-gene related peptide (CGRP) is a vasoactive neuropeptide involved in the pathophysiology ofmigraine. CGRP has been targeted for both preventive and acute treatment of migraine.

Objective: Provide a summary of the most clinically relevant literature surrounding CGRP modulating therapies.

Methods: This update on CGRP modulating therapies includes articles selected as most clinically relevant by theauthors.

Conclusion: CGRP modulating therapies are an exciting new addition to migraine treatment given their safety andtolerability. Additionally, compared to traditional migraine preventive medication these treatments are migrainespecific.Further real-world and clinical data is ongoing to better understand these treatments that continue to gainfavor in the management of migraine.

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CGRP 调节疗法:最新进展。
导言:降钙素基因相关肽(CGRP)是一种血管活性神经肽,与偏头痛的病理生理学有关。CGRP 已成为偏头痛预防和急性治疗的靶向药物:总结与 CGRP 调节疗法相关的临床文献:方法:这篇关于CGRP调节疗法的更新文章包括作者挑选出的与临床最相关的文章:鉴于其安全性和耐受性,CGRP调节疗法是偏头痛治疗领域令人兴奋的新成员。此外,与传统的偏头痛预防药物相比,这些疗法具有偏头痛特异性。目前正在进一步收集真实世界和临床数据,以更好地了解这些在偏头痛治疗中不断获得青睐的疗法。
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来源期刊
ACS Applied Energy Materials
ACS Applied Energy Materials Materials Science-Materials Chemistry
CiteScore
10.30
自引率
6.20%
发文量
1368
期刊介绍: ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.
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