Right atrial and right ventricular strain: prognostic value depends on the severity of tricuspid regurgitation.

IF 6.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS European Heart Journal - Cardiovascular Imaging Pub Date : 2024-11-27 DOI:10.1093/ehjci/jeae182
Elizabeth Curtis, Léo Lemarchand, K Charlotte Lee, Elena Galli, Guillaume L'Official, Vincent Auffret, Guillaume Leurent, Emmanuel Oger, Erwan Donal
{"title":"Right atrial and right ventricular strain: prognostic value depends on the severity of tricuspid regurgitation.","authors":"Elizabeth Curtis, Léo Lemarchand, K Charlotte Lee, Elena Galli, Guillaume L'Official, Vincent Auffret, Guillaume Leurent, Emmanuel Oger, Erwan Donal","doi":"10.1093/ehjci/jeae182","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>Assessing right heart function is challenging, particularly when significant tricuspid regurgitation (TR) is present. Amongst available echocardiographic techniques for assessment, literatures suggest that strain imaging may be more reliable and less susceptible to loading conditions. Thus, we aimed to assess the validity of right atrial (RA) and right ventricular (RV) strain relative to conventional metrics as well as their utility in predicting patient outcomes in TR.</p><p><strong>Methods and results: </strong>We studied 262 consecutive patients (mean age 74 ± 11.2 years, 53% male) who underwent same-day echocardiography and right heart catheterization between 2018 and 2023. We compared right heart strain to traditional metrics of RV function and subsequently correlated RA and RV strain to heart failure (HF)-related death or hospitalization, whichever came first. Over a mean follow-up of 34 ± 15 months, there were 103 deaths and HF hospitalizations. Both RA strain and RV strain were correlated with echocardiographic and invasive measures of right heart function. Across all patients, preserved RA strain was associated with lower risk of adverse outcomes [hazard ratio (HR) 0.763, 95% confidence interval (CI) 0.618-0.943]. Similarly, preserved RV strain was correlated with better outcomes, although this was only statistically significant in patients without severe TR or pulmonary hypertension (HR 2.450, 95% CI 1.244-4.825). Moreover, abnormal ratios of RV strain to pulmonary pressures and RV size were significantly correlated with adverse outcomes (P < 0.05 each).</p><p><strong>Conclusion: </strong>RA and RV strain are independently correlated with echocardiographic and invasive measures of cardiac function. Moreover, preserved RA and RV strain is likely associated with better clinical outcomes.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1734-1742"},"PeriodicalIF":6.7000,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Heart Journal - Cardiovascular Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ehjci/jeae182","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

Aims: Assessing right heart function is challenging, particularly when significant tricuspid regurgitation (TR) is present. Amongst available echocardiographic techniques for assessment, literatures suggest that strain imaging may be more reliable and less susceptible to loading conditions. Thus, we aimed to assess the validity of right atrial (RA) and right ventricular (RV) strain relative to conventional metrics as well as their utility in predicting patient outcomes in TR.

Methods and results: We studied 262 consecutive patients (mean age 74 ± 11.2 years, 53% male) who underwent same-day echocardiography and right heart catheterization between 2018 and 2023. We compared right heart strain to traditional metrics of RV function and subsequently correlated RA and RV strain to heart failure (HF)-related death or hospitalization, whichever came first. Over a mean follow-up of 34 ± 15 months, there were 103 deaths and HF hospitalizations. Both RA strain and RV strain were correlated with echocardiographic and invasive measures of right heart function. Across all patients, preserved RA strain was associated with lower risk of adverse outcomes [hazard ratio (HR) 0.763, 95% confidence interval (CI) 0.618-0.943]. Similarly, preserved RV strain was correlated with better outcomes, although this was only statistically significant in patients without severe TR or pulmonary hypertension (HR 2.450, 95% CI 1.244-4.825). Moreover, abnormal ratios of RV strain to pulmonary pressures and RV size were significantly correlated with adverse outcomes (P < 0.05 each).

Conclusion: RA and RV strain are independently correlated with echocardiographic and invasive measures of cardiac function. Moreover, preserved RA and RV strain is likely associated with better clinical outcomes.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
右心房和右心室应变:预后价值取决于三尖瓣反流的严重程度。
目的:评估右心功能具有挑战性,尤其是在存在严重三尖瓣反流(TR)的情况下。在现有的超声心动图评估技术中,文献表明应变成像可能更可靠,且不易受负荷条件的影响。因此,我们旨在评估 RA 和 RV 应变相对于传统指标的有效性,以及它们在预测 TR 患者预后方面的实用性:我们研究了 2018 年至 2023 年间接受过当天超声心动图和右心导管检查的 262 名连续患者(平均年龄 74 ± 11.2 岁,53% 为男性)。我们将右心应变与传统的 RV 功能指标进行了比较,随后将 RA 和 RV 应变与心力衰竭(HF)相关的死亡或住院(以先到者为准)进行了关联:在平均 34 ± 15 个月的随访期间,共有 103 人死亡或因心衰住院。RA 和 RV 应变均与右心功能的超声心动图和有创测量相关。在所有患者中,保留 RA 应变与较低的不良预后风险相关(HR 0.763,95% CI 0.618-0.943)。同样,保留的 RV 应变与较好的预后相关,但这只对无严重 TR 或肺动脉高压的患者有统计学意义(HR 2.450,95% CI 1.244-4.825)。此外,RV 应变与肺动脉压力和 RV 大小的异常比率与不良预后显著相关(P < 0.05):结论:RA 和 RV 应变与超声心动图和有创心功能测量结果独立相关。此外,保留 RA 和 RV 应变可能与更好的临床预后相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
European Heart Journal - Cardiovascular Imaging
European Heart Journal - Cardiovascular Imaging CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
11.60
自引率
9.70%
发文量
708
审稿时长
4-8 weeks
期刊介绍: European Heart Journal – Cardiovascular Imaging is a monthly international peer reviewed journal dealing with Cardiovascular Imaging. It is an official publication of the European Association of Cardiovascular Imaging, a branch of the European Society of Cardiology. The journal aims to publish the highest quality material, both scientific and clinical from all areas of cardiovascular imaging including echocardiography, magnetic resonance, computed tomography, nuclear and invasive imaging. A range of article types will be considered, including original research, reviews, editorials, image focus, letters and recommendation papers from relevant groups of the European Society of Cardiology. In addition it provides a forum for the exchange of information on all aspects of cardiovascular imaging.
期刊最新文献
From Myocarditis to Myocardial Infarction: A Case of Anomalous Left Main Coronary Artery in a 17-Year-Old Girl. Mitral transcatheter edge-to-edge repair for complex anatomy: double-orifice mitral valve. Cardiac Calcified Amorphous Tumor: A Diagnostic and Clinical Challenge. Glycogen Storage Disease Type IIIa: A Rare Cause of Myocardial Hypertrophy with Multisystem Involvement. A Rare Complication of Infective Endocarditis: Left Ventricular Pseudoaneurysm Masquerading as Severe Mitral Regurgitation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1