Reverse takotsubo cardiomyopathy in the setting of small bowel obstruction: a case report

Daniel Bishev, Hussein A. Noureldine, Fernando Ortiz
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Abstract

Stress cardiomyopathy refers to a syndrome of acute but reversible left ventricular dysfunction, often triggered by emotional or physical stress. Reverse takotsubo cardiomyopathy is an uncommon variant that occurs in about 5% of cases. Classically, it has been known to be following a catecholamine surge due to physical or emotional stress. This case highlights the importance for physicians to be aware of the possibility of developing a stress cardiomyopathy in patients with acute intrabdominal processes. 41-year-old Caucasian female with was admitted with an acute small bowel obstruction. After failing conservative management, it was decided to proceed with surgery. After induction with anesthesia but prior to the surgeons first incision, the patient developed a tachyarrhythmia with hemodynamic compromise requiring the surgery to be aborted. That evening, she developed chest pain with concerns for an acute coronary syndrome. She was taken urgently to the for invasive angiography which demonstrated reverse takotsubo. Intra-abdominal processes and intubation have previously been reported be catalyst for this disease process. This patient had multiple stressors including mechanical bowel obstruction and anesthesia after failing conservative management. The diagnosis was confirmed by coronary angiography and left ventriculogram, and followed up with repeat outpatient echocardiography. A case of small bowel obstruction that developed reverse takotsubo preceded by sustained ventricular tachycardia after intubation. The patient did well and had complete recovery cardiac function. Risk factors and underlining mechanism for the different variants of stress cardiomyopathy are not well understood, further investigation is warranted.
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小肠梗阻引起的反向塔克次氏心肌病:病例报告
应激性心肌病是指一种急性但可逆的左心室功能障碍综合征,通常由情绪或身体应激引发。反向拓扑心肌病是一种不常见的变异型心肌病,发生率约为 5%。通常情况下,它是在身体或情绪压力导致儿茶酚胺激增后发生的。本病例强调,医生必须意识到急性腹内过程患者发生应激性心肌病的可能性。 41 岁的白种女性因急性小肠梗阻入院。在保守治疗无效后,决定进行手术治疗。麻醉诱导后,但在外科医生第一次切开之前,患者出现了快速性心律失常,血流动力学受到影响,需要中止手术。当晚,她出现胸痛,担心是急性冠状动脉综合征。她被紧急送往医院进行有创血管造影检查,结果显示为反向 Takotsubo。 据报道,腹腔内过程和插管是这种疾病的催化剂。该患者在保守治疗失败后,承受了机械性肠梗阻和麻醉等多重压力。经冠状动脉造影和左心室造影确诊,并在门诊再次进行超声心动图检查。 一例小肠梗阻患者在插管后出现持续室性心动过速,继而发展为反向 Takotsubo。患者表现良好,心功能完全恢复。应激性心肌病不同变异的风险因素和基本机制尚不十分清楚,需要进一步研究。
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