Extensive Extragenital Lichen Sclerosus-Like Lesions in a Patient with Junctional Epidermolysis Bullosa

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-07-15 DOI:10.4103/idoj.idoj_503_23
Smriti Gupta, Sanjeev Handa, Debajyoti Chatterjee, Dipankar De, Rahul Mahajan
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Abstract

Epidermolysis bullosa (EB) is a heterogeneous group of genetic disorders characterized by the formation of blisters and/or at the sites of trauma. These heal with post-inflammatory hypopigmentation, scarring, or milia formation. We hereby present a child who presented with widespread hypopigmented atrophic areas, blistering at trauma-prone sites, and nail dystrophy. The significance of this particular case lies in the challenge of distinguishing between epidermolysis bullosa (EB) and bullous extragenital lichen sclerosus et atrophicus (LSA).
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一名交界性表皮松解症患者的大面积眶外硬皮病样皮损
大疱性表皮松解症(Epidermolysis bullosa,EB)是一类以在创伤部位形成水疱和/或为特征的遗传性疾病。痊愈后会出现炎症后色素减退、瘢痕或粟粒疹。我们在此介绍一名患有广泛色素减退性萎缩区、外伤易发部位水疱和甲营养不良的患儿。这个特殊病例的意义在于,它是区分大疱性表皮松解症(EB)和大疱性眶外硬化性萎缩性苔藓(LSA)的难题。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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