Influence of Breast Milk Contamination with Chlororganic Pesticides on the Formation of Microflora Colonization Resistance in Newborns Gastrointestinal Tract in Conditions of Osh

Abstract

Determining the state of the intestinal biocenosis in newborns is given great attention, since the normalization of the biocenosis of the intestinal tract is important in the processes of digestion and the formation of immunity. Research purpose: to study the effect of contamination of breast milk (BM) with organochlorine pesticides on the formation of colonization resistance of the intestinal microflora in the early neonatal period in newborn children living in Osh. To carry out the research, the intestinal microflora of 63 newborns whose mothers lived in the conditions of Osh was studied. Qualitative studies of obligate and facultative flora were carried out on 3rd-4th and 6th-7th days. In the early neonatal period, formation of colonization resistance does not occur during the first week in BM newborns under conditions of environmental pollution with organochlorine pesticides, since it is due to the concentration of organochlorine pesticides in the breast milk of nursing women. The relationship between the content of eubiotics in the gastrointestinal tract of lactating women and the content of microflora in breast milk has been identified; recommendations have been developed for pregnant and lactating women to maintain colonization resistance of the microflora in breast milk of lactating women.