Bilateral renal artery stenosis in pediatric patient with Post-Streptococcal Glomerulonephritis in children: A case report

Nieken Susanti, Irma Nur Sukmawati
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Abstract

The immune-complex mediated inflammation known as post-streptococcal glomerulonephritis (PSGN) was once thought to be one of the most common causes of acute nephritis in children. In this case, we present a 12-year-old girl experiencing symptoms of cough phlegm, congested breath, change of urine color, decreased urine production, as well swelling in the area face and legs after experiencing fever, pain swallowing, cough, and runny nose 3 weeks before admission. On physical examination, the pressure blood was 130/80 mmHg. In addition, the palpebral and extremity were edema bilateral, hyperemia of the tonsil and pharynx, enlarged tonsils T2/T3, and detritus were found. Laboratory and Imaging Tests: hematology; leukocytes 12,930, albumin 2.4 g/dl, on urinalysis, obtained urine cloudy, brownish, leukocyturia, hematuria, and proteinuria, there was also an increase in ASTO titers, abdominal ultrasound found bilateral renal artery stenosis and nephritis bilateral acute. The patient in this case presented with bilateral renal artery stenosis, which is a rare finding in PSGN cases. Management of PSGN include bed rest, low salt diet, fluid balance, as well supportive treatment with IVFD D5 ½ NS 15 drops/min (micro), Antibiotics injection of Ceftriaxone 1 gram/12 hours on the first day and continued with oral Erythromycin 4x500mg, injection prednisolone 3x1, injection Furosemide 1x1 amp, oral spironolactone and sublingual nifedipine, and hypoalbuminemia correction. Prognosis in patients with the given GNAPS governance optimally will give good results.
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链球菌性肾小球肾炎后儿童患者的双侧肾动脉狭窄:病例报告
链球菌感染后肾小球肾炎(PSGN)这种免疫复合物介导的炎症曾被认为是儿童急性肾炎最常见的病因之一。本病例中,一名 12 岁女孩在入院前 3 周出现发热、吞咽疼痛、咳嗽、流鼻涕等症状,随后出现咳嗽痰多、鼻塞、尿色改变、尿量减少以及面部和腿部浮肿。体格检查时,血压为 130/80 mmHg。此外,双侧睑部和四肢水肿,扁桃体和咽部充血,扁桃体T2/T3肿大,并有脱屑。实验室和影像学检查:血液学检查;白细胞 12930,白蛋白 2.4 g/dl,尿常规检查,尿液混浊,呈棕色,白细胞尿,血尿,蛋白尿,ASTO 滴度也有增加,腹部超声检查发现双侧肾动脉狭窄,双侧急性肾炎。本例患者出现双侧肾动脉狭窄,这在 PSGN 病例中并不多见。PSGN 的治疗包括卧床休息、低盐饮食、体液平衡,以及 IVFD D5 ½ NS 15 滴/分(微量)的支持治疗,第一天注射头孢曲松 1 克/12 小时的抗生素,并继续口服红霉素 4x500 毫克,注射泼尼松龙 3x1,注射呋塞米 1x1 amp,口服螺内酯和舌下含服硝苯地平,以及纠正低白蛋白血症。预后良好的患者在接受给定的 GNAPS 治疗后会取得良好的效果。
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