Leukemia Cancer Cells Segmentation and Classification using Machine Learning

M. Rajamanickam, Dr. C. Meenakshi
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Abstract

Determining the aim of the project is to detect the leukemia at earlier stage with the help of image processing techniques. Leukemia means blood cancer which is featured by the uncontrolled and abnormal production of white blood cells (leukocytes) by the bone marrow in the blood. Acute Lymphoblastic Leukemia (ALL) is a type of leukemia which is more common in children. The term Acute‟ means that leukemia can progress quickly and if not treated may lead to fatal death within few months. Due to its non specific nature of the symptoms and signs of ALL leads wrong diagnosis. Even hematologist finds it difficult to classify the leukemia cells, there manual classification of blood cells is not only time consuming but also inaccurate. Therefore, early identification of leukemia yields in providing the appropriate treatment to the patient. Detection through images is fast and cheap method as there is no special need of equipment for lab testing. We have focused on the changes in the geometry of cells like area, perimeter and statistical parameters like mean and standard deviation which separates white blood cells from other blood components using processing tools like MATLAB. After recognizing its statistical properties, types of leukemia will be identified based on the irregularities in the shape.
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利用机器学习对白血病癌细胞进行分割和分类
确定该项目的目的是借助图像处理技术及早发现白血病。白血病指的是血癌,其特征是骨髓在血液中不受控制地异常制造白细胞(白血球)。急性淋巴细胞白血病(ALL)是白血病的一种,在儿童中更为常见。所谓 "急性",是指白血病进展迅速,如果不及时治疗,可能会在几个月内导致死亡。由于急性白血病的症状和体征没有特异性,导致诊断错误。即使是血液学专家也很难对白血病细胞进行分类,人工对血细胞进行分类不仅费时,而且不准确。因此,早期识别白血病有助于为患者提供适当的治疗。通过图像进行检测是一种快速、廉价的方法,因为不需要特殊的实验室检测设备。我们使用 MATLAB 等处理工具,重点关注细胞几何形状的变化,如面积、周长以及平均值和标准偏差等统计参数,从而将白细胞与其他血液成分区分开来。在识别其统计属性后,将根据形状的不规则性来确定白血病的类型。
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