A - 44 A Comparison of Multi-Domain Clinical Assessment Outcomes in Older Adults Following Concussion

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-07-06 DOI:10.1093/arclin/acae052.44
N. Ramirez, A. J. Zynda, C. Perry, C. Burley, S. Patel, H. Guercio, N. Bunker, J. French, A. Trbovich, M. Collins, A. Kontos
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Abstract

To examine differences in demographics, medical history, injury characteristics, and multidomain clinical assessment outcomes between different age groups of older adults following concussion. This prospective study included participants aged 50+ years with a diagnosed concussion (<12 months) who presented to a specialty concussion clinic. Participants completed a clinical intake/interview (e.g., demographics) and a multidomain clinical assessment comprising symptoms (Clinical Profile Screen [CP-Screen]), cognitive (Repeatable Battery for the Assessment of Neuropsychological Status [RBANS]), psychological health (Patient Health Questionnaire-9 [PHQ-9], Generalized Anxiety Disoder-7 [GAD-7]), vestibular/ocular (Vestibular/Ocular Motor Screen [VOMS]), and quality of life (Neurological Quality of Life [Neuro-QoL]) at an initial visit. Older adults aged 50–59 and 60+ years were compared using independent samples t-tests, X2 tests, and analyses of covariance. 76 participants (M = 59.6¬ ± 6.3 years, 55.3% female) were included, 41 (53.9%) aged 50–59 and 35 (46.1%) aged 60+ years. The 50–59-year group had a greater proportion of females (68.3% vs. 40.0%, p = 0.01) and a history of anxiety (39.0% vs. 17.1%, p = 0.036). The 50–59-year group had worse Neuro-QoL (F[1, 72] = 5.1, p = 0.03, ηp2 = 0.10), RBANS recall (F[1, 72] = 7.1, p < 0.01, ηp2 = 0.09), RBANS fluency (F[1, 72] = 5.0, p = 0.03, ηp2 = 0.06), and RBANS list recognition (F[1, 72] = 4.1, p = 0.04, ηp2 = 0.06), controlling for sex and history of anxiety. This study demonstrated that adults aged 50–59 years were more likely to be female and have a history of anxiety compared to adults 60+ years. Interestingly, older adults 50–59 years demonstrated greater perceived difficulties in their cognitive abilities post-concussion, which was reflected in impairments on cognitive testing compared to adults 60+ years.
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A - 44 比较老年人脑震荡后的多领域临床评估结果
研究不同年龄组的老年人在脑震荡后的人口统计学、病史、损伤特征和多领域临床评估结果之间的差异。 这项前瞻性研究包括年龄在 50 岁以上、确诊脑震荡(<12 个月)并到脑震荡专科门诊就诊的参与者。参与者完成了临床接诊/访谈(例如,人口统计学)和多指标问卷调查、人口统计学)和多领域临床评估,包括症状(临床概况筛查 [CP-Screen])、认知(神经心理状态评估可重复电池 [RBANS])、心理健康(患者健康问卷-9 [PHQ-9]、广泛性焦虑症-7 [GAD-7])、前庭/眼部(前庭/眼部运动筛查 [VOMS])和生活质量(神经系统生活质量 [Neuro-QoL])。采用独立样本 t 检验、X2 检验和协方差分析对 50-59 岁和 60 岁以上的老年人进行了比较。 76名参与者(中=59.6±6.3岁,55.3%为女性)中有41人(53.9%)年龄在50-59岁之间,35人(46.1%)年龄在60岁以上。50-59 岁组中女性比例更高(68.3% 对 40.0%,p = 0.01),且有焦虑史(39.0% 对 17.1%,p = 0.036)。50-59岁组的神经-生活质量(Neuro-QoL)(F[1,72] = 5.1,p = 0.03,ηp2 = 0.10)、RBANS回忆(F[1,72] = 7.1,p < 0.01,ηp2 = 0.09)、RBANS流畅度(F[1,72] = 5.0,p = 0.03,ηp2 = 0.06)和 RBANS 列表识别(F[1,72] = 4.1,p = 0.04,ηp2 = 0.06),并控制了性别和焦虑史。 这项研究表明,与 60 岁以上的成年人相比,50-59 岁的成年人更有可能是女性且有焦虑史。有趣的是,与 60 岁以上的成年人相比,50-59 岁的老年人在脑震荡后的认知能力方面遇到了更大的困难,这反映在认知测试上。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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