Accessibility and Affordability Issues for Renal Replacement Therapy Remain Challenges in Resource-Limited Healthcare Settings: A Case Report and Critique of Literature for Chronic Kidney and End-Stage Renal Disease

Janvier Nzayikorera
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Abstract

Chronic kidney disease (CKD) continues to be a global public health problem. Globally, the prevalence of CKD is approximately 8–16% in the general population. Most patients with CKD advance to kidney failure and require dialysis or kidney transplantation. Screening for CKD, diagnosing CKD, treating CKD and its consequences to stop its progression, and renal replacement therapy (RRT) are all parts of comprehensive CKD care. A 28-year-old male presented with complaints of awareness of his heart beating, abdomen and lower limb swelling, and generalised body weakness for 2 days. His blood pressure was 222/147 mmHg on admission day. Six days post-admission, he displayed violent chest pain and dyspnoea, along with profound generalised body swelling. Laboratory studies revealed creatinine of 22.49 mg/dL (0.6–1.1), urea of 236.5 mg/dL (10.0–50), albumin of 2.15 mg/dL (3.8–5.1), potassium of 7.19 mmol/L (3.5–5.5), and haemoglobin of 6.2 g/dL (8.0–17.0). The diagnoses of uremic pericarditis, pulmonary oedema, hyperkalaemia, hypertensive emergency, and normochromic anaemia secondary to end-stage renal diseases were made. He qualified for the RRT. CKD is a serious, non-communicable disease that is commonly encountered in clinical practice in both developed and developing countries and needs the utmost attention. RRT is crucial for comprehensive CKD management; however, in resource-limited healthcare settings, RRT is non-accessible and non-affordable. The lack of RRT marks the mistreatment of patients with renal diseases by the global healthcare system. The author calls for designing new strategies that aim to ensure equitable accessibility and affordability for RRT globally.
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在资源有限的医疗环境中,肾脏替代疗法的可及性和可负担性问题仍是一项挑战:慢性肾病和终末期肾病病例报告和文献综述
慢性肾脏病(CKD)仍然是一个全球性的公共卫生问题。在全球范围内,慢性肾脏病的发病率约占总人口的 8-16%。大多数慢性肾脏病患者会发展到肾衰竭,需要透析或肾移植。筛查慢性肾功能衰竭、诊断慢性肾功能衰竭、治疗慢性肾功能衰竭及其后果以阻止其进展以及肾脏替代疗法(RRT)都是慢性肾功能衰竭综合治疗的组成部分。一名 28 岁的男性前来就诊,主诉两天来一直感觉心脏跳动、腹部和下肢肿胀、全身无力。入院当天血压为 222/147 mmHg。入院六天后,他出现剧烈胸痛和呼吸困难,全身浮肿。实验室检查显示肌酐为 22.49 mg/dL(0.6-1.1),尿素为 236.5 mg/dL(10.0-50),白蛋白为 2.15 mg/dL(3.8-5.1),钾为 7.19 mmol/L(3.5-5.5),血红蛋白为 6.2 g/dL(8.0-17.0)。他被诊断为尿毒症性心包炎、肺水肿、高钾血症、高血压急症和终末期肾病继发的正常色素性贫血。他符合接受 RRT 的条件。慢性肾脏病是一种严重的非传染性疾病,在发达国家和发展中国家的临床实践中都很常见,需要引起高度重视。RRT 对于全面治疗慢性肾脏病至关重要;然而,在资源有限的医疗环境中,RRT 无法获得,也负担不起。缺乏 RRT 标志着全球医疗保健系统对肾病患者的虐待。作者呼吁制定新的战略,旨在确保全球范围内 RRT 的公平可及性和可负担性。
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