Vitamin D: A Key Factor in Prostate Health

Lana Lekic, E. Alibegović, Jasna Rahimić, Bojan Pavlović, Ana Pavlović, Aida Hamzić-Mehmedbašić, Aldijana Mahmutović Milićević, Nehra Mosorović, Emil Mujkić, Asja Šarić, Dino Alibegović
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Abstract

This study examines the correlation between vitamin D levels and the severity of symptoms and quality of life in patients with benign prostatic hyperplasia (BPH). A total of 125 participants were categorized based on their prostate symptoms (mild, moderate, and severe) and vitamin D levels (deficient, insufficient, and optimal). Among those with mild symptoms (n=60), 37.93% were vitamin D deficient, 44.11% had insufficient vitamin D, and 54.83% had optimal levels. For moderate symptoms (n=55), 44.82% were deficient, 47.05% had insufficient, and 41.93% had optimal vitamin D levels. In severe cases (n=10), 17.04% were deficient, 8.82% had insufficient, and 3.22% had optimal vitamin D levels. Overall, 23.02% of participants were deficient, 27.02% had insufficient, and 49.6% had optimal vitamin D levels. Quality of life assessments revealed that 56.8% of participants reported a good quality of life, with 46.66% of these being vitamin D deficient, 57.57% insufficient, and 61.29% optimal. An indifferent quality of life was noted by 29.6% of participants, with 28.57% deficient, 27.27% insufficient, and 29.03% optimal vitamin D levels. A very poor quality of life was reported by 13.6% of participants, with 21.42% deficient, 15.15% insufficient, and 9.67% optimal vitamin D levels. These results indicate a potential association between higher vitamin D levels and improved prostate symptoms and quality of life in BPH patients. Further research is needed to establish causality and underlying mechanisms.
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维生素 D:前列腺健康的关键因素
本研究探讨了维生素 D 水平与良性前列腺增生症(BPH)患者的症状严重程度和生活质量之间的相关性。共有 125 名参与者根据其前列腺症状(轻度、中度和重度)和维生素 D 水平(缺乏、不足和最佳)进行了分类。在轻度症状者(人数=60)中,37.93%缺乏维生素D,44.11%维生素D不足,54.83%达到最佳水平。中度症状患者(55 人)中,44.82% 缺乏维生素 D,47.05% 维生素 D 不足,41.93% 维生素 D 水平最佳。在重度病例(10 人)中,17.04% 的人缺乏维生素 D,8.82% 的人维生素 D 不足,3.22% 的人维生素 D 水平最佳。总体而言,23.02%的参与者缺乏维生素D,27.02%的参与者维生素D不足,49.6%的参与者维生素D水平达到最佳。生活质量评估显示,56.8% 的参与者表示生活质量良好,其中 46.66% 缺乏维生素 D,57.57% 不足,61.29% 最佳。29.6%的参与者表示生活质量不高,其中 28.57%的人缺乏维生素 D,27.27%的人维生素 D 水平不足,29.03%的人维生素 D 水平最佳。13.6%的参与者表示生活质量很差,其中 21.42% 的人缺乏维生素 D,15.15% 的人维生素 D 水平不足,9.67% 的人维生素 D 水平最佳。这些结果表明,维生素 D 水平的提高与良性前列腺增生症患者前列腺症状和生活质量的改善之间存在潜在联系。要确定因果关系和内在机制,还需要进一步的研究。
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