Suspected Symptomatic Infected Native Aortic Aneurysm Turns Out To Be Aortic Tumour Originating From Metastatic Cancer of Unknown Primary: A Case Report and Review of Literature

IF 1.4 Q3 PERIPHERAL VASCULAR DISEASE EJVES Vascular Forum Pub Date : 2024-01-01 DOI:10.1016/j.ejvsvf.2024.06.002
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Abstract

Introduction

The non-specific clinical presentation of a primary aortic tumour may mimic infectious processes. Together with its rarity, this resemblance can complicate timely identification and pose diagnostic challenges.

Report

The case of a 77 year old male patient complaining of abdominal pain radiating to the back, fatigue, and loss of appetite for a month, is presented. Contrast enhanced computed tomography showed a 47 mm infrarenal aortic aneurysm with peripheral enhancement. With suspicion of an infected native aortic aneurysm, open aortic repair was performed using a bovine pericardial Y prosthesis. The intra-operative biopsy revealed a malignant undifferentiated neoplasm, which later turned out to originate from metastatic cancer of unknown primary. The patient died six months later following comprehensive and extensive oncological treatment, which included radiotherapy and chemotherapy.

Discussion

Given the scarcity of literature and challenges in classification, treatment recommendations rely on a multidisciplinary approach, involving surgery, radiotherapy, and chemotherapy. Despite the lack of established guidelines, early intervention, even in metastatic cases, may improve clinical outcomes. Surgical resection, whenever appropriate, is advocated, as it not only alleviates symptoms, but intra-operative histological sampling also aids in obtaining a definitive diagnosis.

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疑似有症状的感染性原发性主动脉瘤竟是源于原发灶不明的转移性癌症的主动脉瘤:病例报告与文献综述
导言原发性主动脉肿瘤的非特异性临床表现可能与感染过程相似。该病例是一名 77 岁的男性患者,主诉腹痛放射至背部、乏力和食欲不振一个月。对比增强型计算机断层扫描显示,肾下主动脉瘤直径为 47 毫米,周边增强。由于怀疑是受感染的原发性主动脉瘤,医生使用牛心包Y型假体进行了主动脉开放修补术。术中活检发现了恶性未分化肿瘤,后来证实是原发灶不明的转移癌。讨论鉴于文献资料的匮乏和分类方面的挑战,治疗建议依赖于多学科方法,包括手术、放疗和化疗。尽管缺乏既定的指南,但早期干预,即使是转移性病例,也可改善临床预后。在适当的情况下,主张进行手术切除,因为这不仅能缓解症状,而且术中组织学取样也有助于获得明确诊断。
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来源期刊
EJVES Vascular Forum
EJVES Vascular Forum Medicine-Surgery
CiteScore
1.50
自引率
0.00%
发文量
145
审稿时长
102 days
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